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Math @ Duke
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Publications [#379923] of Dorothy Buck
Papers Published
- Buck, D; Flapan, E, Predicting knot or catenane type of site-specific recombination products.,
Journal of molecular biology, vol. 374 no. 5
(December, 2007),
pp. 1186-1199 [doi]
(last updated on 2026/01/21)
Abstract: Site-specific recombination on supercoiled circular DNA yields a variety of knotted or catenated products. Here, we present a topological model of this process and characterize all possible products of the most common substrates: unknots, unlinks, and torus knots and catenanes. This model tightly prescribes the knot or catenane type of previously uncharacterized data. We also discuss how the model helps to distinguish products of distributive recombination and, in some cases, determine the order of processive recombination products.
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dept@math.duke.edu
ph: 919.660.2800
fax: 919.660.2821
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Mathematics Department
Duke University, Box 90320
Durham, NC 27708-0320
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