Math @ Duke
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Publications [#322682] of Guillermo Sapiro
Papers Published
- Kim, J; Duchin, Y; Sapiro, G; Vitek, J; Harel, N, Clinical deep brain stimulation region prediction using regression forests from high-field MRI,
Proceedings - International Conference on Image Processing, ICIP, vol. 2015-December
(December, 2015),
pp. 2480-2484, IEEE, ISBN 9781479983391 [doi]
(last updated on 2025/02/02)
Abstract: This paper presents a prediction framework of brain subcortical structures which are invisible on clinical low-field MRI, learning detailed information from ultrahigh-field MR training data. Volumetric segmentation of Deep Brain Stimulation (DBS) structures within the Basal ganglia is a prerequisite process for reliable DBS surgery. While ultrahigh-field MR imaging (7 Tesla) allows direct visualization of DBS targeting structures, such ultrahigh-fields are not always clinically available, and therefore the relevant structures need to be predicted from the clinical data. We address the shape prediction problem with a regression forest, non-linearly mapping predictors to target structures with high confidence, exploiting ultrahigh-field MR training data. We consider an application for the subthalamic nucleus (STN) prediction as a crucial DBS target. Experimental results on Parkinson's patients validate that the proposed approach enables reliable estimation of the STN from clinical 1.5T MRI.
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