Math @ Duke
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Publications [#363581] of Sayan Mukherjee
Papers Published
- Mahato, CK; Mukherjee, S; Kundu, M; Pramanik, A, Pyrrolidine-Oxadiazolone Conjugates as Organocatalysts in Asymmetric Michael Reaction.,
The Journal of organic chemistry, vol. 84 no. 2
(January, 2019),
pp. 1053-1063 [doi]
(last updated on 2025/02/21)
Abstract: Pyrrolidine-oxadiazolone based organocatalysts are envisaged, synthesized, and utilized for asymmetric Michael reactions. Results of the investigations suggest that some of the catalysts are indeed efficient for stereoselective 1,4-conjugated Michael additions (dr: >97:3, ee up to 99%) in high chemical yields (up to 97%) often in short reaction time. As an extension, one enantiopure Michael adduct has been utilized to synthesize optically active octahydroindole.
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