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Amir H. Rezvani, Professor in Psychiatry and Behavioral Sciences

Amir H. Rezvani
Contact Info:
Office Location:  323 Foster St., Durham, NC 27701
Office Phone:  (919) 668-1880
Email Address:   send me a message
Web Page:   http://faculty.duhs.duke.edu/faculty/info?pid=5055

Teaching (Fall 2024):

  • Psy 197fs.01, Addiction and substance abuse Synopsis
    East duke 204a, TuTh 10:05 AM-11:20 AM
  • Psy 197fs.02, Addiction and substance abuse Synopsis
    East duke 204a, TuTh 11:45 AM-01:00 PM
Office Hours:

By appointment.
Education:

Ph.D.University of Illinois, Urbana-Champaign1983
Representative Publications   (More Publications)   (search)

  1. Rezvani, AH; Cauley, M; Xiao, Y; Kellar, KJ; Levin, ED (2013). Effects of chronic sazetidine-A, a selective α4β2 neuronal nicotinic acetylcholine receptors desensitizing agent on pharmacologically-induced impaired attention in rats.. Psychopharmacology (Berl), 226(1), 35-43. [23100170], [doi]  [abs]
  2. Levin, ED; Cauley, M; Rezvani, AH (2013). Improvement of attentional function with antagonism of nicotinic receptors in female rats.. Eur J Pharmacol, 702(1-3), 269-274. [23399762], [doi]  [abs]
  3. Hussmann, GP; Turner, JR; Lomazzo, E; Venkatesh, R; Cousins, V; Xiao, Y; Yasuda, RP; Wolfe, BB; Perry, DC; Rezvani, AH; Levin, ED; Blendy, JA; Kellar, KJ (2012). Chronic sazetidine-A at behaviorally active doses does not increase nicotinic cholinergic receptors in rodent brain.. Journal of Pharmacology and Experimental Therapeutics, 343(2), 441-450. [22899752], [doi]  [abs]
  4. Rezvani, AH; Cauley, MC; Johnson, EC; Gatto, GJ; Levin, ED (2012). Effects of AZD3480, a neuronal nicotinic acetylcholine receptor agonist, and donepezil on dizocilpine-induced attentional impairment in rats.. Psychopharmacology (Berl), 223(3), 251-258. [22526540], [doi]  [abs]
  5. Swartzwelder, NA; Risher, ML; Abdelwahab, SH; D'Abo, A; Rezvani, AH; Levin, ED; Wilson, WA; Swartzwelder, HS; Acheson, SK (2012). Effects of ethanol, Δ(9)-tetrahydrocannabinol, or their combination on object recognition memory and object preference in adolescent and adult male rats.. Neurosci Lett, 527(1), 11-15. [22959891], [doi]  [abs]
  6. Rezvani, AH; Lawrence, AJ; Arolfo, MP; Levin, ED; Overstreet, DH (2012). Novel medication targets for the treatment of alcoholism: preclinical studies.. Recent Pat Cns Drug Discov, 7(2), 151-162. [22574676], [doi]  [abs]
  7. Johnson, JE; Slade, S; Wells, C; Petro, A; Sexton, H; Rezvani, AH; Brown, ML; Paige, MA; McDowell, BE; Xiao, Y; Kellar, KJ; Levin, ED (2012). Assessing the effects of chronic sazetidine-A delivery on nicotine self-administration in both male and female rats.. Psychopharmacology (Berl), 222(2), 269-276. [22297831], [doi]  [abs]
  8. Bartley, PC; Rezvani, AH (2012). Alcohol and cognition - consideration of age of initiation, usage patterns and gender: a brief review.. Curr Drug Abuse Rev, 5(2), 87-97. [22455507], [doi]  [abs]
  9. Rezvani, AH; Timofeeva, O; Sexton, HG; DeCuir, D; Xiao, Y; Gordon, CJ; Kellar, KJ; Levin, ED (2012). Effects of sazetidine-A, a selective α4β2* nicotinic receptor desensitizing agent, on body temperature regulation in mice and rats.. Eur J Pharmacol, 682(1-3), 110-117. [22387853], [doi]  [abs]
  10. Levin, ED; Slade, S; Wells, C; Cauley, M; Petro, A; Vendittelli, A; Johnson, M; Williams, P; Horton, K; Rezvani, AH (2011). Threshold of adulthood for the onset of nicotine self-administration in male and female rats.. Behav Brain Res, 225(2), 473-481. [21854810], [doi]  [abs]
  11. Cippitelli, A; Rezvani, AH; Robinson, JE; Eisenberg, L; Levin, ED; Bonaventure, P; Motley, ST; Lovenberg, TW; Heilig, M; Thorsell, A (2011). The novel, selective, brain-penetrant neuropeptide Y Y2 receptor antagonist, JNJ-31020028, tested in animal models of alcohol consumption, relapse, and anxiety.. Alcohol, 45(6), 567-576. [21145691], [doi]  [abs]
  12. Levin, ED; Bushnell, PJ; Rezvani, AH (2011). Attention-modulating effects of cognitive enhancers.. Pharmacol Biochem Behav, 99(2), 146-154. [21334367], [doi]  [abs]
  13. Rezvani, AH; Cauley, M; Sexton, H; Xiao, Y; Brown, ML; Paige, MA; McDowell, BE; Kellar, KJ; Levin, ED (2011). Sazetidine-A, a selective α4β2 nicotinic acetylcholine receptor ligand: effects on dizocilpine and scopolamine-induced attentional impairments in female Sprague-Dawley rats.. Psychopharmacology (Berl), 215(4), 621-630. [21274704], [doi]  [abs]
  14. Galici, R; Rezvani, AH; Aluisio, L; Lord, B; Levin, ED; Fraser, I; Boggs, J; Welty, N; Shoblock, JR; Motley, ST; Letavic, MA; Carruthers, NI; Dugovic, C; Lovenberg, TW; Bonaventure, P (2011). JNJ-39220675, a novel selective histamine H3 receptor antagonist, reduces the abuse-related effects of alcohol in rats.. Psychopharmacology (Berl), 214(4), 829-841. [21086115], [doi]  [abs]
  15. Rezvani, AH; Slade, S; Wells, C; Petro, A; Lumeng, L; Li, T-K; Xiao, Y; Brown, ML; Paige, MA; McDowell, BE; Rose, JE; Kellar, KJ; Levin, ED (2010). Effects of sazetidine-A, a selective alpha4beta2 nicotinic acetylcholine receptor desensitizing agent on alcohol and nicotine self-administration in selectively bred alcohol-preferring (P) rats.. Psychopharmacology (Berl), 211(2), 161-174. [20535453], [doi]  [abs]
  16. AH Rezvani, H Sexton, ED Levin (2010). Persistent high alcohol consumption in alcohol-preferring (P) rats results from a lack of normal aversion to alcohol.. Alcohol and alcoholism (Oxford, Oxfordshire), 45(3), 219-22. [doi]  [abs]
  17. Levin, ED; Rezvani, AH; Xiao, Y; Slade, S; Cauley, M; Wells, C; Hampton, D; Petro, A; Rose, JE; Brown, ML; Paige, MA; McDowell, BE; Kellar, KJ (2010). Sazetidine-A, a selective alpha4beta2 nicotinic receptor desensitizing agent and partial agonist, reduces nicotine self-administration in rats.. Journal of Pharmacology and Experimental Therapeutics, 332(3), 933-939. [20007754], [doi]  [abs]
  18. Rezvani, AH; Overstreet, DH; Vaidya, AH; Zhao, B; Levin, ED (2009). Carisbamate, a novel antiepileptic candidate compound, attenuates alcohol intake in alcohol-preferring rats.. Alcohol Clin Exp Res, 33(8), 1366-1373. [19413647], [doi]  [abs]
  19. Tizabi, Y; Getachew, B; Rezvani, AH; Hauser, SR; Overstreet, DH (2009). Antidepressant-like effects of nicotine and reduced nicotinic receptor binding in the Fawn-Hooded rat, an animal model of co-morbid depression and alcoholism.. Progress in Neuro Psychopharmacology & Biological Psychiatry, 33(3), 398-402. [18835320], [doi]  [abs]
  20. Rezvani, AH; Kholdebarin, E; Cauley, MC; Dawson, E; Levin, ED (2009). Attenuation of pharmacologically-induced attentional impairment by methylphenidate in rats.. Pharmacology, Biochemistry, and Behavior, 92(1), 141-146. [19041337], [doi]  [abs]
  21. Rezvani, AH; Kholdebarin, E; Brucato, FH; Callahan, PM; Lowe, DA; Levin, ED (2009). Effect of R3487/MEM3454, a novel nicotinic alpha7 receptor partial agonist and 5-HT3 antagonist on sustained attention in rats.. Progress in Neuro Psychopharmacology & Biological Psychiatry, 33(2), 269-275. [19110025], [doi]  [abs]
  22. Levin, ED; Petro, A; Rezvani, AH; Pollard, N; Christopher, NC; Strauss, M; Avery, J; Nicholson, J; Rose, JE (2009). Nicotinic alpha7- or beta2-containing receptor knockout: effects on radial-arm maze learning and long-term nicotine consumption in mice.. Behav Brain Res, 196(2), 207-213. [18831991], [doi]  [abs]
  23. Levin, ED; Slade, S; Johnson, M; Petro, A; Horton, K; Williams, P; Rezvani, AH; Rose, JE (2008). Ketanserin, a 5-HT2 receptor antagonist, decreases nicotine self-administration in rats.. Eur J Pharmacol, 600(1-3), 93-97. [18950618], [doi]  [abs]
  24. Rezvani, AH; Eddins, D; Slade, S; Hampton, DS; Christopher, NC; Petro, A; Horton, K; Johnson, M; Levin, ED (2008). Neonatal 6-hydroxydopamine lesions of the frontal cortex in rats: persisting effects on locomotor activity, learning and nicotine self-administration.. Neuroscience, 154(3), 885-897. [18511204], [doi]  [abs]
  25. Rezvani, AH; Tizabi, Y; Getachew, B; Hauser, SR; Caldwell, DP; Hunter, C; Levin, ED (2008). Chronic nicotine and dizocilpine effects on nicotinic and NMDA glutamatergic receptor regulation: interactions with clozapine actions and attentional performance in rats.. Progress in Neuro Psychopharmacology & Biological Psychiatry, 32(4), 1030-1040. [18343006], [doi]  [abs]
  26. Schramm-Sapyta, NL; Kingsley, MA; Rezvani, AH; Propst, K; Swartzwelder, HS; Kuhn, CM (2008). Early ethanol consumption predicts relapse-like behavior in adolescent male rats.. Alcohol Clin Exp Res, 32(5), 754-762. [18336637], [doi]  [abs]
  27. Rezvani, AH; Kholdebarin, E; Dawson, E; Levin, ED (2008). Nicotine and clozapine effects on attentional performance impaired by the NMDA antagonist dizocilpine in female rats.. The International Journal of Neuropsychopharmacology, 11(1), 63-70. [17295931], [doi]  [abs]
  28. Levin, ED; Rezvani, AH (2007). Nicotinic interactions with antipsychotic drugs, models of schizophrenia and impacts on cognitive function.. Biochemical Pharmacology, 74(8), 1182-1191. [17714691], [doi]  [abs]
  29. Rezvani, AH; Overstreet, DH; Cleves, M; Parsian, A (2007). Further genetic characterization of the fawn-hooded (FH/Wjd) rat, an animal model of comorbid depression and alcoholism.. Psychiatric Genetics, 17(2), 77-83. [17413446], [doi]  [abs]
  30. ED Levin, SS Lawrence, A Petro, K Horton, AH Rezvani, FJ Seidler, TA Slotkin (2007). Adolescent vs. adult-onset nicotine self-administration in male rats: duration of effect and differential nicotinic receptor correlates.. Neurotoxicology and teratology, 29(4), 458-65. [doi]  [abs]
  31. Patra, B; Overstreet, DH; Rezvani, AH; Cleves, M; Parsian, A (2007). Analysis of alcohol-related phenotypes in F2 progeny derived from FH/Wjd and ACI/N rat strains reveals independent measures and sex differences.. Behavioural Brain Research, 177(1), 37-44. [17161877], [doi]  [abs]
  32. Rezvani, AH; Overstreet, DH; Levin, ED; Rosenthal, DI; Kordik, CP; Reitz, AB; Vaidya, AH (2007). Effects of atypical anxiolytic N-phenyl-2-[1-[3-(2-pyridinylethynyl)benzoyl]-4-piperidine]acetamide (JNJ-5234801) on alcohol intake in alcohol-preferring P rats.. Alcoholism, Clinical and Experimental Research, 31(1), 57-63. [17207102], [doi]  [abs]
  33. Overstreet, DH; Rezvani, AH; Djouma, E; Parsian, A; Lawrence, AJ (2007). Depressive-like behavior and high alcohol drinking co-occur in the FH/WJD rat but appear to be under independent genetic control.. Neuroscience and Biobehavioral Reviews, 31(1), 103-114. [16982094], [doi]  [abs]
  34. Overstreet, DH; Rezvani, AH; Cowen, M; Chen, F; Lawrence, AJ (2006). Modulation of high alcohol drinking in the inbred Fawn-Hooded (FH/Wjd) rat strain: implications for treatment.. Addiction Biology, 11(3-4), 356-373. [16961764], [doi]  [abs]
  35. AH Rezvani, DP Caldwell, ED Levin (2006). Chronic nicotine interactions with clozapine and risperidone and attentional function in rats.. Progress in neuro-psychopharmacology & biological psychiatry, 30(2), 190-7. [doi]  [abs]
  36. Rezvani, AH; Caldwell, DP; Levin, ED (2006). Chronic nicotine interactions with clozapine and risperidone and attentional function in rats.. Progress in Neuro Psychopharmacology & Biological Psychiatry, 30(2), 190-197. [16310917], [doi]  [abs]
  37. Levin, ED; McClernon, FJ; Rezvani, AH (2006). Nicotinic effects on cognitive function: behavioral characterization, pharmacological specification, and anatomic localization.. Psychopharmacology, 184(3-4), 523-539. [16220335], [doi]  [abs]
  38. Levin, ED; Rezvani, AH (2006). Nicotinic-antipsychotic drug interactions and cognitive function.. Exs, 98, 185-205. [17019889], [doi]  [abs]
  39. Barron, S; White, A; Swartzwelder, HS; Bell, RL; Rodd, ZA; Slawecki, CJ; Ehlers, CL; Levin, ED; Rezvani, AH; Spear, LP (2005). Adolescent vulnerabilities to chronic alcohol or nicotine exposure: findings from rodent models.. Alcoholism, Clinical and Experimental Research, 29(9), 1720-1725. [16205372], [doi]  [abs]
  40. Rezvani, AH; Caldwell, DP; Levin, ED (2005). Nicotinic-serotonergic drug interactions and attentional performance in rats.. Psychopharmacology, 179(3), 521-528. [15682310], [doi]  [abs]
  41. Levin, ED; Tizabi, Y; Rezvani, AH; Caldwell, DP; Petro, A; Getachew, B (2005). Chronic nicotine and dizocilpine effects on regionally specific nicotinic and NMDA glutamate receptor binding.. Brain Research, 1041(2), 132-142. [15829222], [doi]  [abs]
  42. Rezvani, AH; Levin, ED (2004). Adolescent and adult rats respond differently to nicotine and alcohol: motor activity and body temperature.. International Journal of Developmental Neuroscience : the Official Journal of the International Society for Developmental Neuroscience, 22(5-6), 349-354. [15380834], [doi]  [abs]
  43. Rezvani, AH; Levin, ED (2004). Nicotine-antipsychotic drug interactions and attentional performance in female rats.. European Journal of Pharmacology, 486(2), 175-182. [14975706], [doi]  [abs]
  44. Levin, ED; Rezvani, AH; Montoya, D; Rose, JE; Swartzwelder, HS (2003). Adolescent-onset nicotine self-administration modeled in female rats.. Psychopharmacology, 169(2), 141-149. [12764575], [doi]  [abs]
  45. Rezvani, AH; Levin, ED (2003). Nicotine-alcohol interactions and attentional performance on an operant visual signal detection task in female rats.. Pharmacology, Biochemistry, and Behavior, 76(1), 75-83. [13679219], [doi]  [abs]
  46. Rezvani, AH; Overstreet, DH; Perfumi, M; Massi, M (2003). Plant derivatives in the treatment of alcohol dependency.. Pharmacology, Biochemistry, and Behavior, 75(3), 593-606. [12895677], [doi]  [abs]
  47. Rezvani, AH; Levin, ED (2003). Nicotinic-glutamatergic interactions and attentional performance on an operant visual signal detection task in female rats.. European Journal of Pharmacology, 465(1-2), 83-90. [12650836], [doi]  [abs]
  48. Chen, F; Rezvani, AH; Lawrence, AJ (2003). Autoradiographic quantification of neurochemical markers of serotonin, dopamine and opioid systems in rat brain mesolimbic regions following chronic St John's wort treatment.. Naunyn Schmiedeberg'S Archives of Pharmacology, 367(2), 126-133. [12595953], [doi]  [abs]
  49. Overstreet, DH; Keung, W-M; Rezvani, AH; Massi, M; Lee, DYW (2003). Herbal remedies for alcoholism: promises and possible pitfalls.. Alcoholism, Clinical and Experimental Research, 27(2), 177-185. [12605067], [doi]  [abs]
  50. Rezvani, AH; Bushnell, PJ; Levin, ED (2002). Effects of nicotine and mecamylamine on choice accuracy in an operant visual signal detection task in female rats.. Psychopharmacology, 164(4), 369-375. [12457266], [doi]  [abs]
  51. Levin, ED; Rezvani, AH (2002). Nicotinic treatment for cognitive dysfunction.. Current Drug Targets. Cns and Neurological Disorders, 1(4), 423-431. [12769614], [doi]  [abs]
  52. Rezvani, AH; Levin, ED (2002). Nicotine-alcohol interactions and cognitive function in rats.. Pharmacology, Biochemistry, and Behavior, 72(4), 865-872. [12062576], [doi]  [abs]
  53. AH Rezvani, PJ Bushnell, JM Burkholder, HB Glasgow Jr, ED Levin (2002). Specificity of cognitive impairment from Pfiesteria piscicida exposure in rats: attention and visual function versus behavioral plasticity.. Neurotoxicology and teratology, 23(6), 609-16.  [abs]
  54. Rezvani, AH; Parsian, A; Overstreet, DH (2002). The Fawn-Hooded (FH/Wjd) rat: a genetic animal model of comorbid depression and alcoholism.. Psychiatric Genetics, 12(1), 1-16. [11901354], [doi]  [abs]
  55. Gordon, CJ; Rezvani, AH (2001). Genetic selection of rats with high and low body temperatures.. Journal of Thermal Biology, 26(3), 223-229. [11240229], [doi]  [abs]
  56. Rezvani, AH; Levin, ED (2001). Cognitive effects of nicotine.. Biological Psychiatry, 49(3), 258-267. [11230877], [doi]  [abs]
  57. 1. Rezvani A.H., and Levin E.D. Cognitive effects of nicotine. Biological Psychiatry 49: 258-267, 2001..
  58. 2. Matthews D.B., Overstreet D.H. Rezvani A.H., Devaud L.L., and Morrow A.L. Effects of sweetened ethanol solutions on ethanol self-administration and blood ethanol levels. Pharmacol. Biochem. Behav. 68:13-21, 2001..
  59. 3. Gordon C.J., and Rezvani A.H. Genetic selection of rats with high and low body temperatures. J. Thermal Biology 26:23-29, 2001..
  60. 4. Rezvani AH, Bushnell PJ, Burkholder JM, Glasgow HB, and Levin ED. Specificity of cognitive impairment from Pfiesteria piscicida exposure in rats: Attention and visual function vs behavioral plasticity. Neurotoxicology and Teratology 23:609-616 2001..
  61. 6. Levin ED, Rezvani AH. Nicotine involvement in memory function of rats. In: Nicotinic receptors in the nervous system Levin E.D. ed. Pp167-178, CRC Press, 2001..
  62. Levin, ED; Mead, T; Rezvani, AH; Rose, JE; Gallivan, C; Gross, R (2000). The nicotinic antagonist mecamylamine preferentially inhibits cocaine vs. food self-administration in rats.. Physiology & Behavior, 71(5), 565-570. [11239676], [doi]  [abs]
  63. ED Levin, AH Rezvani, NC Christopher, HB Glasgow Jr, NJ Deamer-Melia, JM Burkholder, VC Moser, K Jensen (2000). Rapid neurobehavioral analysis of Pfiesteria piscicida effects in juvenile and adult rats.. Neurotoxicology and teratology, 22(4), 533-40.  [abs]
  64. Levin, ED; Rezvani, AH (2000). Development of nicotinic drug therapy for cognitive disorders.. European Journal of Pharmacology, 393(1-3), 141-146. [10771007], [doi]  [abs]
  65. Farren, CK; Rezvani, AH; Overstreet, D; O'Malley, S (2000). Combination pharmacotherapy in alcoholism: a novel treatment approach.. Cns Spectrums, 5(2), 70-76. [18297000], [doi]  [abs]
  66. Rezvani, AH; Overstreet, DH; Mason, GA; Janowsky, DS; Hamedi, M; Clark, E; Yang, Y (2000). Combination pharmacotherapy: a mixture of small doses of naltrexone, fluoxetine, and a thyrotropin-releasing hormone analogue reduces alcohol intake in three strains of alcohol-preferring rats.. Alcohol and Alcoholism (Oxford, Oxfordshire), 35(1), 76-83. [10684782], [doi]  [abs]
  67. AH Rezvani, DH Overstreet, Y Yang, E Clark Jr (1999). Attenuation of alcohol intake by extract of Hypericum perforatum (St. John's Wort) in two different strains of alcohol-preferring rats.. Alcohol and alcoholism (Oxford, Oxfordshire), 34(5), 699-705.  [abs]
  68. Overstreet, DH; Kampov-Polevoy, AB; Rezvani, AH; Braun, C; Bartus, RT; Crews, FT (1999). Suppression of alcohol intake by chronic naloxone treatment in P rats: tolerance development and elevation of opiate receptor binding.. Alcoholism, Clinical and Experimental Research, 23(11), 1761-1771. [10591592], [doi]  [abs]
  69. DH Overstreet, AH Rezvani, A Parsian (1999). Behavioural features of alcohol-preferring rats: focus on inbred strains.. Alcohol and alcoholism (Oxford, Oxfordshire), 34(3), 378-85.  [abs]
  70. Cowen, MS; Rezvani, AH; Jarrott, B; Lawrence, AJ (1999). Ethanol consumption by Fawn-Hooded rats following abstinence: effect of naltrexone and changes in mu-opioid receptor density.. Alcoholism, Clinical and Experimental Research, 23(6), 1008-1014. [10397284], [doi]  [abs]
  71. Tizabi, Y; Overstreet, DH; Rezvani, AH; Louis, VA; Clark, E; Janowsky, DS; Kling, MA (1999). Antidepressant effects of nicotine in an animal model of depression.. Psychopharmacology, 142(2), 193-199. [10102772], [doi]  [abs]
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