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| Publications [#274968] of John S. March
search PubMed.Papers Published
- JS March, HL Leonard and SE Swedo (1995). Neuropsychiatry of obsessive-compulsive disorder in children and adolescents.. Compr Ther, 21(9), 507-512. [8565438]
(last updated on 2016/01/27)
Abstract: Physicians understanding of the pathobiobiology, diagnosis, and treatment of OCD in children and adolescents closely resembles that for OCD in adults. Moreover, it is now clear that OCD is a neurobehavioral disorder involving dysregulation in links between cortical and subcortical circuitry that is substantially influenced by serotonergic neurotransmission. Although current treatments are not generally curative, given a correct diagnosis and the skillful combination of pharmacotherapy with a serotonin reuptake inhibitor and focused cognitive-behavioral psychotherapy, most children can be helped to resume a normal developmental trajectory.
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