Publications [#254409] of Keith E. Whitfield

Journal Articles

1. Whitfield, KE; Grant, J; Ravich-Scherbo, I; Marytuina, T; Iboutolina, A (1999). Genetic and environmental influences on forced expiratory volume in midlife : A cross-cultural replication. Experimental Aging Research, 25(3), 255-265. [doi]
   (last updated on 2017/07/31)

   Abstract:
   Previous research has shown that forced expiratory volume (FEV) is a useful predictor of remaining life in older adults. The present analyses are an attempt to replicate results from a study of Swedish twins which demonstrated substantial heritability of FEV with a sample of middle-aged Russian adult twins. Data were collected from 116 pairs of Russian twins (monozygote=71, dizygotic=45, mean age=40.9 years). Phenotypic correlations between FEV, age, gender, height, and cigarette consumption (in pack years) were all significant, ranging from - .72 to .31. After the effects of age, gender, height, and smoking were partialled out of FEV, quantitative genetic analyses were conducted. Shared environmental effects were significant, accounting for 47% of the variance in FEV. Genetic effects, which accounted for about 28% of the variance, could be dropped from the model without a significant decrease in the fit. These results are discussed in relation to previous research conducted in other countries.