| Publications [#343771] of Marc A. Sommer
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- Yarossi, M; Quivira, F; Dannhauer, M; Sommer, MA; Brooks, DH; Erdoǧmuş, D; Tunik, E (2019). An experimental and computational framework for modeling multi-muscle responses to transcranial magnetic stimulation of the human motor cortex. International IEEE/EMBS Conference on Neural Engineering, NER, 2019-March, 1122-1125. [doi]
(last updated on 2024/04/19)
Abstract: Current knowledge of coordinated motor control of multiple muscles is derived primarily from invasive stimulation-recording techniques in animal models. Similar studies are not generally feasible in humans, so a modeling framework is needed to facilitate knowledge transfer from animal studies. We describe such a framework that uses a deep neural network model to map finite element simulation of transcranial magnetic stimulation induced electric fields (E-fields) in motor cortex to recordings of multi-muscle activation. Critically, we show that model generalization is improved when we incorporate empirically derived physiological models for E-field to neuron firing rate and low-dimensional control via muscle synergies.
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