Publications [#252978] of Warren H. Meck

Journal Articles

1. Paule, MG; Meck, WH; McMillan, DE; McClure, GY; Bateson, M; Popke, EJ; Chelonis, JJ; Hinton, SC (1999). The use of timing behaviors in animals and humans to detect drug and/or toxicant effects.. Neurotoxicology and Teratology, 21(5), 491-502. [10492384], [doi]
   (last updated on 2020/02/09)

   Abstract:
   Behavioral paradigms applicable for use in both human and nonhuman subjects for investigating aspects of timing behavior are presented with a view towards exploring their strengths, weaknesses, and utility in a variety of experimental situations. Tri-peak, peak interval, differential reinforcement of low rate responding, and temporal response differentiation procedures are highlighted. In addition, the application of timing tasks in preclinical and clinical settings is discussed: pharmacological manipulations are providing information on the neurotransmitters involved and species differences; normative data for children are being developed; and noninvasive imaging procedures are being employed in adult human subjects to explore the involvement of specific brain areas.