Publications [#277289] of Redford B. Williams

Journal Articles

1. Roy, A; Berman, J; Williams, R; Kuhn, C; Gonzalez, B (2002). Higher levels of CSF homovanillic acid in recently abstinent cocaine-dependent patients.. The American Journal of Psychiatry, 159(6), 1053-1055. [doi]
   (last updated on 2023/06/01)

   Abstract:
   OBJECTIVE: The authors examined an index of dopaminergic neurotransmission in recently abstinent cocaine-dependent patients. METHOD: CSF concentrations of the dopamine metabolite homovanillic acid (HVA) were determined in 30 recently abstinent cocaine-dependent patients and 69 healthy comparison subjects. RESULTS: The cocaine-dependent patients had a significantly higher mean concentration of CSF HVA than did the healthy comparison group. CONCLUSIONS: Recently abstinent cocaine-dependent patients may show dysregulation of the central dopaminergic system.