Publications [#273386] of Richard S. Keefe

Journal Articles

1. Siegel, BV; Trestman, RL; O'Flaithbheartaigh, S; Mitropoulou, V; Amin, F; Kirrane, R; Silverman, J; Schmeidler, J; Keefe, RS; Siever, LJ (1996). D-amphetamine challenge effects on Wisconsin Card Sort Test. Performance in schizotypal personality disorder.. Schizophrenia Research, 20(1-2), 29-32. [doi]
   (last updated on 2024/01/01)

   Abstract:
   The authors assessed the effects on Wisconsin Card Sort (WCST) performance and psychiatric symptoms of 30 mg d-amphetamine, a dopamine and norepinephrine agonist, vs placebo in nine patients with schizotypal personality disorder (SPD). Patients, particularly those who made more perseverative errors, demonstrated amphetamine-associated improvement on WCST performance. The data in this preliminary study suggest that some of the cognitive dysfunction present in SPD may improve with amphetamine challenge.