Publications [#253323] of Terrie E. Moffitt

Journal Articles

1. Caspi, A; Moffitt, TE (2006). Gene-environment interactions in psychiatry: joining forces with neuroscience.. Nature reviews. Neuroscience, 7(7), 583-590. (This paper was reviewed in Faculty1000 of Medicine, scored “9 exceptional”.). [16791147], [doi]
   (last updated on 2024/04/23)

   Abstract:
   Gene-environment interaction research in psychiatry is new, and is a natural ally of neuroscience. Mental disorders have known environmental causes, but there is heterogeneity in the response to each causal factor, which gene-environment findings attribute to genetic differences at the DNA sequence level. Such findings come from epidemiology, an ideal branch of science for showing that a gene-environment interactions exist in nature and affect a significant fraction of disease cases. The complementary discipline of epidemiology, experimental neuroscience, fuels gene-environment hypotheses and investigates underlying neural mechanisms. This article discusses opportunities and challenges in the collaboration between psychiatry, epidemiology and neuroscience in studying gene-environment interactions.