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Pratt School of Engineering
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Publications [#112879] of G Vann V. Bennett

Papers Published

  1. S Lambert, V Bennett, From anemia to cerebellar dysfunction. A review of the ankyrin gene family., European journal of biochemistry / FEBS, GERMANY, vol. 211 no. 1-2 (January, 1993), pp. 1-6, ISSN 0014-2956
    (last updated on 2003/02/18)

    Abstract:
    The focus of this review is on the ankyrin gene family, key elements in the interaction of the spectrin-based membrane skeleton with the plasma membrane in a variety of tissues and multicellular organisms. The structure/function relationships of ankyrin molecules are reviewed, illustrating how these proteins are uniquely suited to serve as adaptors between the membrane skeleton and a number of integral membrane proteins. Advances in the understanding of ankyrin biology in the brain are discussed and used to show how ankyrins may be involved in the establishment and/or maintenance of specialized plasma membrane domains. Finally, recent research in hematological and neurological disorders are reviewed, suggesting that ankyrins have a role in the development of human disease.

    Keywords:
    Animals • Ankyrins • Cell Membrane • Erythrocyte Membrane • Genes • Humans • Multigene Family • Protein Binding • physiology • physiology* • ultrastructure


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