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Publications [#112918] of G Vann V. Bennett

Papers Published

  1. SE Lux, KM John, V Bennett, Analysis of cDNA for human erythrocyte ankyrin indicates a repeated structure with homology to tissue-differentiation and cell-cycle control proteins., Nature, vol. 344 no. 6261 (March, 1990), pp. 36-42, ISSN 0028-0836 [doi]
    (last updated on 2013/05/16)

    Abstract:
    Analysis of complementary DNA for human erythroid ankyrin indicates that the mature protein contains 1,880 amino acids comprising an N-terminal domain binding integral membrane proteins and tubulin, a central domain binding spectrin and vimentin, and an acidic C-terminal 'regulatory' domain containing an alternatively spliced sequence missing from ankyrin variant 2.2. The N-terminal domain is almost entirely composed of 22 tandem 33-amino-acid repeats. Similar repeats are found in yeast and invertebrate proteins involved in cell-cycle control and tissue differentiation.

    Keywords:
    Amino Acid Sequence • Animals • Ankyrins • Base Sequence • Blood Proteins • Cell Cycle • Cell Differentiation • Cloning, Molecular • DNA • Erythrocytes • Fungal Proteins • Humans • Invertebrates • Membrane Proteins • Molecular Sequence Data • Molecular Weight • Proto-Oncogenes • Repetitive Sequences, Nucleic Acid • Sequence Homology, Nucleic Acid • Viral Proteins • Yeasts • genetics • genetics*


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