Publications [#283950] of Piotr E. Marszalek

Papers Published

1. Kim, M; Wang, C-C; Benedetti, F; Rabbi, M; Bennett, V; Marszalek, PE, Nanomechanics of streptavidin hubs for molecular materials., Adv Mater, vol. 23 no. 47 (December, 2011), pp. 5684-5688 [22102445], [doi]
   (last updated on 2023/06/01)

   Abstract:
   A new strategy is reported for creating protein-based nanomaterials by genetically fusing large polypeptides to monomeric streptavidin and exploiting the propensity of streptavidin monomers(SM) to self-assemble into stable tetramers. We have characterized the mechanical properties of streptavidin-linked structures and measured, for the first time, the mechanical strength of streptavidin tetramers themselves. Using streptavidin tetramers as molecular hubs offers a unique opportunity to create a variety of well-defined, self-assembled protein-based (nano)materials with unusual mechanical properties.