Publications [#64952] of Sidney A Simon

Papers Published

1. McIntosh, T.J. and Magid, A.D. and Simon, S.A., Repulsive interactions between uncharged bilayers. Hydration and fluctuation pressures for monoglycerides, Biophys. J. (USA), vol. 55 no. 5 (1989), pp. 897 - 904
   (last updated on 2007/04/15)

   Abstract:
   Pressure versus distance relations have been obtained for solid (gel) and neat (liquid-crystalline) phase uncharged lipid bilayers by the use of X-ray diffraction analysis of osmotically stressed monoglyceride aqueous dispersions and multilayers. For solid phase monoelaidin bilayers, the interbilayer repulsive pressure decays exponentially from a bilayer separation of ~7 Å at an applied pressure of 3×10⁷ dyn/cm² to a separation of ~11 Å at zero applied pressure, where an excess water phase forms. The decay length is ~1.3 Å, which is similar to the value previously measured for gel phase phosphatidylcholine bilayers. This implies that the decay length of the hydration pressure does not depend critically on the presence of zwitterionic head groups in the bilayer surface. For liquid-crystalline monocaprylin, the repulsive pressure versus distance curve has two distinct regions

   Keywords:
   cellular biophysics;lipid bilayers;