Center for Biomolecular and Tissue Engineering Center for Biomolecular and Tissue Engineering
Pratt School of Engineering
Duke University

 HOME > pratt > CBTE    Search Help Login pdf version printable version 

Publications [#61758] of Joseph A. Izatt

Papers Published

  1. Barton, J.K. and Welch, A.J. and Izatt, J.A., Investigating pulsed dye laser-blood vessel interaction with color Doppler optical coherence tomography, Opt. Express (USA), vol. 3 no. 6 (14)
    (last updated on 2007/04/13)

    Abstract:
    A noninvasive method of imaging laser irradiated blood vessels has been achieved using Color Doppler Optical Coherence Tomography (CDOCT). This method may increase understanding of the mechanisms behind treatment of vascular disorders. The CDOCT system used a 1280 nm center wavelength superluminescent diode. A 585 nm, 360 μs pulsed dye laser was used to irradiate hamster dorsal skin flap window preparations. Irradiation sites were imaged with CDOCT prior to, immediately after, and 24 hours after laser irradiation. The processed CDOCT signal provided an estimate of the blood flow velocity. An increase in the blood vessel backscattered signal was observed as blood or vessel walls were coagulated. A decrease in damaged blood vessel reflectivity occurred after twenty four hours

    Keywords:
    backscatter;biological effects of laser radiation;biological techniques;blood;Doppler measurement;dye lasers;light coherence;optical tomography;reflectivity;skin;


Duke University * Pratt * CBTE * Reload * Login