Publications [#147452] of Bruce M. Klitzman

Papers Published

1. CP Demas, R Vann, E Ritter, RS Sepka, B Klitzman, WJ Barwick, Decreased thrombogenicity of vascular prostheses following gas denucleation by hydrostatic pressure., Plastic and reconstructive surgery, UNITED STATES, vol. 82 no. 6 (December, 1988), pp. 1042-5, ISSN 0032-1052
   (last updated on 2007/01/02)

   Abstract:
   The high rate of thrombosis of 1.0-mm polytetrafluoroethylene (PTFE) grafts has limited their use in microvascular surgery. One possible reason for this is the blood-gas interface due to entrapped air in the interstices. The present study examines the effect on patency rates of elimination of this blood-gas interface by high pressurization. Comparing pressurized and nonpressurized grafts in the same animals showed a patency rate of 100 percent at 7 days for treated grafts, while the control (nonpressurized) grafts had all clotted by 1 hour. The implications for microvascular surgery as well as vascular surgery in general are discussed.

   Keywords:
   Animals • Blood Vessel Prosthesis* • Embolism, Air • Graft Occlusion, Vascular • Hydrostatic Pressure • Male • Polytetrafluoroethylene* • Rats • Vascular Patency • prevention & control*