Research Interests for Nenad Bursac

Bursac's research interests include embryonic and adult stem cell therapies for heart and muscle disease. Cardiac and skeletal muscle tissue engineering. Cardiac electrophysiology and arrhythmias. Genetic modifications of stem and somatic cells. Micropatterning of proteins and hydrogels.

Keywords:

Stem cells, tissue engineering, electrophysiology, microfabrication, genetic engineering

Areas of Interest:

Stem cell therapies for heart disease
Tissue engineering/regenerative medicine
Cardiac electrophysiology/arrhythmias
Micropatterning and microfluidics
In vitro model systems
Skeletal muscle function

Recent Publications   (search)

1. D. M. Pedrotty and R. Y. Klinger and R. D. Kirkton and N. Bursac, Cardiac fibroblast paracrine factors alter impulse conduction and ion channel expression of neonatal rat cardiomyocytes, Cardiovascular Research, vol. 83 no. 4 (September, 2009), pp. 688 -- 697, ISSN 0008-6363 [abs]
2. L. C. Mcspadden and R. D. Kirkton and N. Bursac, Electrotonic loading of anisotropic cardiac monolayers by unexcitable cells depends on connexin type and expression level, American Journal Of Physiology-cell Physiology, vol. 297 no. 2 (August, 2009), pp. C339 -- C351, ISSN 0363-6143 [abs]
3. N. Badie and N. Bursac, Novel Micropatterned Cardiac Cell Cultures with Realistic Ventricular Microstructure, Biophysical Journal, vol. 96 no. 9 (May, 2009), pp. 3873 -- 3885, ISSN 0006-3495 [abs]
4. W. N. Bian and N. Bursac, Engineered skeletal muscle tissue networks with controllable architecture, Biomaterials, vol. 30 no. 7 (March, 2009), pp. 1401 -- 1412, ISSN 0142-9612 [abs]
5. N. Badle and N. Bursac, Micropatterned Ventricular Slice: Role of Realistic Tissue Microstructure In Impulse Conduction, Circulation, vol. 118 no. 18 (October, 2008), pp. S493 -- S493, ISSN 0009-7322