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| Publications [#368338] of Piotr E. Marszalek
Papers Published
- Marszalek, PE, Capturing intrinsic nanomechanics of allostery.,
Biophysical Journal, vol. 121 no. 23
(December, 2022),
pp. 4415-4416 [doi]
(last updated on 2023/06/01)
Abstract: The Hsp70 chaperone exploits allosteric communication between its substrate binding domain and its nucleotide binding domain to regulate the loading and release of misfolded polypeptides in an ATP-hydrolysis-dependent manner. In this issue of Biophysical Journal, Singh, Rief, and Žoldák report an exquisitely detailed study of the nanomechanical aspects of the allosteric mechanism in DnaK, an Escherichia coli heat shock protein 70 chaperone.
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