Publications of Charles A. Gersbach    :chronological  alphabetical  combined  bibtex listing:

Papers Published

1. P Perez-Pinera, DD Kocak, CM Vockley, AF Adler, AM Kabadi, LR Polstein, PI Thakore, KA Glass, DG Ousterout, KW Leong, F Guilak, GE Crawford, TE Reddy, CA Gersbach, RNA-Guided Gene Activation by CRISPR-Cas9-Based Transcription Factors, Nature Methods (2013)
2. DG Ousterout, P Perez-Pinera, PI Thakore, AM Kabadi, MT Brown, X Qin, O Fredrigo, V Mouly, JP Tremblay, CA Gersbach, Reading Frame Correction by Targeted Genome Editing Restores Dystrophin Expression in Cells from Duchenne Muscular Dystrophy Patients, Molecular Therapy, vol. 21 no. 9 (2013), pp. 1718-26
3. T Gaj, CA Gersbach, CF Barbas, III, ZFN, TALEN and CRISPR/Cas-Based Methods for Genome Engineering, Trends in Biotechnology, vol. 31 no. 7 (2013), pp. 397-405
4. DW Dumbauld, TT Lee, A Singh, J Scrimgeour, CA Gersbach, EA Zamir, J Fu, CS Chen, JE Curtis, SW Craig, AJ García, How Vinculin Regulates Force Transmission, Proc. Natl. Acad. Sci. USA, vol. 110 no. 24 (2013), pp. 9788-93
5. P. Perez-Pinera, D.G. Ousterout, J.M. Brunger, A.M. Farin, K.A. Glass, F. Guilak, G.E. Crawford, A.J. Hartemink, C.A. Gersbach, Synergistic and Tunable Human Gene Activation by Combinations of Engineered Transcription Factors, Nature Methods, vol. 10 no. 3 (2013), pp. 239-42
6. T.M. Gibson and C.A. Gersbach, The role of single-cell analyses in understanding cell lineage commitment, Biotechnology Journal, vol. 8 no. 4 (2013), pp. 397-407
7. L.R. Polstein and C.A. Gersbach, Light-inducible spatiotemporal control of gene activation by customizable zinc finger transcription factors, Journal of the American Chemical Society, vol. 134 no. 40 (2012), pp. 16480-3
8. P. Perez-Pinera, D.G. Ousterout, and C.A. Gersbach, Advances in targeted genome editing, Current Opinion in Chemical Biology, vol. 16 no. 3-4 (2012), pp. 268-77
9. P. Perez-Pinera, D.G. Ousterout, M.T. Brown, and C.A. Gersbach, Gene targeting to the ROSA26 locus directed by engineered zinc finger nucleases, Nucleic Acids Research, vol. 40 no. 8 (2012), pp. 3741-52
10. M.S. Bhakta, I.M. Henry, D.G. Ousterout, K.T. Das, S.H. Lockwood, J.F. Meckler, M.C. Wallen, A. Zykovich, Y. Yu, H. Leo, L. Xu, C.A. Gersbach, D.J. Segal., Highly Active Zinc Finger Nucleases by Extended Modular Assembly, Genome Research (2012)
11. C.A. Gersbach, T. Gaj, R.M. Gordley, A.C. Mercer, and C.F. Barbas, III., Targeted plasmid integration into the human genome by an engineered zinc-finger recombinase, Nucleic Acids Research, vol. 39 no. 17 (2011), pp. 7868-78
12. T. Gaj, A.C. Mercer, C.A. Gersbach, R.M. Gordley, and C.F. Barbas, III, Structure-guided reprogramming of serine recombinase specificity, Proceedings of the National Academy of Sciences USA, vol. 108 no. 2 (2011), pp. 498-503
13. C.A. Gersbach, T. Gaj, R.M. Gordley, and C.F. Barbas, III., Directed evolution of recombinase specificity by split gene reassembly, Nucleic Acids Research, vol. 38 no. 12 (2010), pp. 4198-206
14. R.M. Gordley, C.A. Gersbach, and C.F. Barbas, III, Synthesis of programmable integrases, Proceedings of the National Academy of Sciences USA, vol. 106 no. 13 (2009), pp. 5053-8
15. C. A. Gersbach, J. E. Phillips, and A. J. Garcia, Genetic engineering for skeletal regenerative medicine, Annual Review of Biomedical Engineering, vol. 9 (2007), pp. 87 - 119, ISSN 1523-9829
16. S. Pregizer, A. Barski, C. A. Gersbach, A. J. Garcia, and B. Frenkel, Identification of novel Runx2 targets in osteoblasts: Cell type-specific BMP-dependent regulation of Tram2, Journal of Cellular Biochemistry, vol. 102 no. 6 (2007), pp. 1458 - 1471, ISSN 0730-2312
17. C. A. Gersbach, S. R. Coyer, J. M. Le Doux, and A. J. Garcia, Biomaterial-mediated retroviral gene transfer using self-assembled monolayers, Biomaterials, vol. 28 no. 34 (2007), pp. 5121 - 5127, ISSN 0142-9612
18. C. A. Gersbach, R. E. Guldberg, and A. J. Garcia, In vitro and in vivo osteoblastic differentiation of BMP-2- and Runx2-engineered skeletal myoblasts, Journal of Cellular Biochemistry, vol. 100 no. 5 (2007), pp. 1324 - 1336, ISSN 0730-2312
19. J. E. Phillips, C. A. Gersbach, and A. J. Garcia, Virus-based gene therapy strategies for bone regeneration, Biomaterials, vol. 28 no. 2 (2007), pp. 211 - 229, ISSN 0142-9612
20. C. A. Gersbach, J. M. Le Doux, R. E. Guldberg, and A. J. Garcia, Inducible regulation of Runx2-stimulated osteogenesis, Gene Therapy, vol. 13 no. 11 (2006), pp. 873 - 882, ISSN 0969-7128
21. J. E. Phillips, C. A. Gersbach, A. M. Wojtowicz, and A. J. Garcia, Glucocorticoid-induced osteogenesis is negatively regulated by Runx2/Cbfa1 serine phosphorylation, Journal of Cell Science, vol. 119 no. 3 (2006), pp. 581 - 591, ISSN 0021-9533
22. M. A. Lan, C. A. Gersbach, K. E. Michael, B. G. Keselowsky, and A. J. Garcia, Myoblast proliferation and differentiation on fibronectin-coated self assembled monolayers presenting different surface chemistries, Biomaterials, vol. 26 no. 22 (2005), pp. 4523 - 4531, ISSN 0142-9612
23. C. A. Gersbach, B. A. Byers, G. K. Pavlath, and A. J. Garcia, Runx2/Cbfa1 stimulates transdifferentiation of primary skeletal myoblasts into a mineralizing osteoblastic phenotype, Experimental Cell Research, vol. 300 no. 2 (2004), pp. 406 - 417, ISSN 0014-4827
24. C. A. Gersbach, B. A. Byers, G. K. Pavlath, R. E. Guldberg, and A. J. Garcia, Runx2/Cbfa1-genetically engineered skeletal myoblasts mineralize collagen scaffolds in vitro, Biotechnology and Bioengineering, vol. 88 no. 3 (2004), pp. 369 - 378, ISSN 0006-3592
25. A. J. Garcia, R. E. Guldberg, B. J. Byers, C. A. Gersbach, and J. E. Phillips, Addressing cell-sourcing limitations with gene therapy, IEEE Engineering in Medicine and Biology Magazine, vol. 22 no. 5 (2003), pp. 65 - 70, ISSN 0739-5175