Publications [#144317] of Christopher R Kelsey

Papers Published

1. CR Kelsey, LB Marks, Somnolence syndrome after focal radiation therapy to the pineal region: case report and review of the literature., Journal of neuro-oncology, Netherlands, vol. 78 no. 2 (June, 2006), pp. 153-6, ISSN 0167-594X
   (last updated on 2008/03/06)

   Abstract:
   Somnolence syndrome classically occurs in children after cranial irradiation for acute lymphocytic leukemia. Symptoms include somnolence, fever, nausea and vomiting, and headache. The authors report a 29 year-old female who developed symptoms compatible with the somnolence syndrome after completing radiation therapy for a benign meningioma near the pineal region. Five weeks after completing conformal radiation therapy (54 Gy), she developed profound fatigue, headaches, and 102-degree fevers. Physical examination and routine laboratory work were unrevealing. Imaging was not performed. Prednisone was prescribed and within 1 week her symptoms had largely resolved. This is the first report of the somnolence syndrome after focal radiation therapy. The possible etiology of the somnolence syndrome is discussed.

   Keywords:
   Adult • Brain Neoplasms • Cranial Irradiation • Fatigue • Female • Fever • Headache • Humans • Meningioma • Nausea • Pineal Gland • Radiotherapy • Sleep Disorders • Syndrome • Treatment Outcome • adverse effects • adverse effects* • complications • etiology • etiology* • radiation effects* • radiotherapy*