Publications [#63191] of Mark W. Dewhirst

Papers Published

1. Page, R.L. and Meyer, R.E. and Thrall, D.E. and Dewhirst, M.W., Cardiovascular and metabolic response of tumour-bearing dogs to whole body hyperthermia, Int. J. Hyperth. (UK), vol. 3 no. 6 (1987), pp. 513 - 25
   (last updated on 2007/04/14)

   Abstract:
   Whole body hyperthermia was induced in older, tumour-bearing dogs using a radiant heat device. Dogs were anaesthetized (thiopental), paralysed (atracurium), and mechanically ventilated (100 per cent O₂) during the heating procedure. Heart rate, systolic/diastolic, and mean arterial blood pressure, and arterial blood gases were monitored throughout the procedure. Serum biochemical parameters, complete blood count, and coagulation profiles were evaluated before, during, and after whole body hyperthermia. Significant increases (p<0.05) were noted in heart rate, systolic pressure, diastolic pressure, and mean arterial pressure during the treatment period. A significant decrease in arterial oxygen partial pressure due to unknown causes occurred during the treatment period. Clinical evidence of cardiac decompensation was not manifested in any dog following whole body hyperthermia

   Keywords:
   biothermics;cardiology;