Anna Mae Diehl, Professor of Medicine

Contact Info:

Office Location:	Ste 1073, GSRB 1
Office Phone:	(919) 684-2366
Email Address:
Web Page:	http://faculty.duhs.duke.edu/faculty/info?pid=9631

Education:

M.D.

Georgetown University

1978

Representative Publications   (More Publications)

1. L Yang, Y Jung, A Omenetti, RP Witek, S Choi, HM Vandongen, J Huang, GD Alpini, AM Diehl, Fate-mapping evidence that hepatic stellate cells are epithelial progenitors in adult mouse livers., Stem cells (Dayton, Ohio), vol. 26 no. 8 (August, 2008), pp. 2104-13, ISSN 1549-4918 [doi]  [abs]
2. X Ouyang, P Cirillo, Y Sautin, S McCall, JL Bruchette, AM Diehl, RJ Johnson, MF Abdelmalek, Fructose consumption as a risk factor for non-alcoholic fatty liver disease., Journal of hepatology, vol. 48 no. 6 (June, 2008), pp. 993-9, ISSN 0168-8278 [doi]  [abs]
3. Y Jung, KD Brown, RP Witek, A Omenetti, L Yang, M Vandongen, RJ Milton, IN Hines, RA Rippe, L Spahr, L Rubbia-Brandt, AM Diehl, Accumulation of hedgehog-responsive progenitors parallels alcoholic liver disease severity in mice and humans., Gastroenterology, vol. 134 no. 5 (May, 2008), pp. 1532-43, ISSN 1528-0012 [doi]  [abs]
4. SF Solga, A Horska, S Hemker, S Crawford, C Diggs, AM Diehl, FL Brancati, JM Clark, Hepatic fat and adenosine triphosphate measurement in overweight and obese adults using 1H and 31P magnetic resonance spectroscopy., Liver international : official journal of the International Association for the Study of the Liver, vol. 28 no. 5 (May, 2008), pp. 675-81, ISSN 1478-3231 [doi]  [abs]
5. A Omenetti, AM Diehl, The adventures of sonic hedgehog in development and repair. II. Sonic hedgehog and liver development, inflammation, and cancer., American journal of physiology. Gastrointestinal and liver physiology, vol. 294 no. 3 (March, 2008), pp. G595-8, ISSN 0193-1857 [doi]  [abs]
6. A Omenetti, Y Popov, Y Jung, SS Choi, RP Witek, L Yang, KD Brown, D Schuppan, AM Diehl, The hedgehog pathway regulates remodelling responses to biliary obstruction in rats., Gut, vol. 57 no. 9 (September, 2008), pp. 1275-82, ISSN 1468-3288 [doi]  [abs]
7. K Yamaguchi, L Yang, S McCall, J Huang, XX Yu, SK Pandey, S Bhanot, BP Monia, YX Li, AM Diehl, Diacylglycerol acyltranferase 1 anti-sense oligonucleotides reduce hepatic fibrosis in mice with nonalcoholic steatohepatitis., Hepatology (Baltimore, Md.), vol. 47 no. 2 (February, 2008), pp. 625-35, ISSN 1527-3350 [doi]  [abs]
8. L Yang, Y Wang, H Mao, S Fleig, A Omenetti, KD Brown, JK Sicklick, YX Li, AM Diehl, Sonic hedgehog is an autocrine viability factor for myofibroblastic hepatic stellate cells., Journal of hepatology, vol. 48 no. 1 (January, 2008), pp. 98-106, ISSN 0168-8278 [doi]  [abs]
9. SV Fleig, SS Choi, L Yang, Y Jung, A Omenetti, HM VanDongen, J Huang, JK Sicklick, AM Diehl, Hepatic accumulation of Hedgehog-reactive progenitors increases with severity of fatty liver damage in mice., Laboratory investigation; a journal of technical methods and pathology, vol. 87 no. 12 (December, 2007), pp. 1227-39, ISSN 1530-0307 [doi]  [abs]
10. MF Abdelmalek, AM Diehl, De novo nonalcoholic fatty liver disease after liver transplantation., Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society, vol. 13 no. 6 (June, 2007), pp. 788-90, ISSN 1527-6465 [doi]
11. K Yamaguchi, L Yang, S McCall, J Huang, XX Yu, SK Pandey, S Bhanot, BP Monia, YX Li, AM Diehl, Inhibiting triglyceride synthesis improves hepatic steatosis but exacerbates liver damage and fibrosis in obese mice with nonalcoholic steatohepatitis., Hepatology (Baltimore, Md.), vol. 45 no. 6 (June, 2007), pp. 1366-74, ISSN 0270-9139 [doi]  [abs]
12. Y Jung, SJ McCall, YX Li, AM Diehl, Bile ductules and stromal cells express hedgehog ligands and/or hedgehog target genes in primary biliary cirrhosis., Hepatology (Baltimore, Md.), vol. 45 no. 5 (May, 2007), pp. 1091-6, ISSN 0270-9139 [doi]  [abs]
13. YX Li, HT Yang, M Zdanowicz, JK Sicklick, Y Qi, TJ Camp, AM Diehl, Fetal alcohol exposure impairs Hedgehog cholesterol modification and signaling., Laboratory investigation; a journal of technical methods and pathology, vol. 87 no. 3 (March, 2007), pp. 231-40, ISSN 0023-6837 [doi]  [abs]
14. C Zhao, W Chen, L Yang, L Chen, SA Stimpson, AM Diehl, PPARgamma agonists prevent TGFbeta1/Smad3-signaling in human hepatic stellate cells., Biochemical and biophysical research communications, vol. 350 no. 2 (November, 2006), pp. 385-91, ISSN 0006-291X [doi]  [abs]
15. JK Sicklick, SS Choi, M Bustamante, SJ McCall, EH Pérez, J Huang, YX Li, M Rojkind, AM Diehl, Evidence for epithelial-mesenchymal transitions in adult liver cells., American journal of physiology. Gastrointestinal and liver physiology, vol. 291 no. 4 (October, 2006), pp. G575-83, ISSN 0193-1857 [doi]  [abs]
16. TL Setji, ND Holland, LL Sanders, KC Pereira, AM Diehl, AJ Brown, Nonalcoholic steatohepatitis and nonalcoholic Fatty liver disease in young women with polycystic ovary syndrome., The Journal of clinical endocrinology and metabolism, vol. 91 no. 5 (May, 2006), pp. 1741-7, ISSN 0021-972X [doi]  [abs]