Curriculum Vitae of Daniel P. Kiehart

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Curriculum Vitae

Daniel P. Kiehart

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4330 French Family Science Cen
Science Drive, Duke University
Durham, NC 277080338

(919) 613-8157, (919) 613-8150 (office)

(email)

Education

Postdoctoral Fellow	Johns Hopkins University Medical School (Thomas D. Pollard, Advisor)	1982
Ph.D.	University of Pennsylvania	1979
B.A.	University of Pennsylvania	1973

Areas of Research: Biophysical approaches to cellular, molecular and developmental biology

Areas of Interest: morphogenesis
wound healing
motor protein structure and function
cytoskeleton
molecular structure
phylogeny of gene families

Professional Experience / Employment History

Duke University: Chair, Department of Biology, July 01, 2007 - present; Professor, Department of Biology, July 2000 to present

Duke University Medical Center: Professor, Department of Cell Biology, July 2000 to present

Duke Unversity Medical Center: Associate Professor, Department of Cell Biology, 1992-2000

Harvard University: Associate Professor, Department of Cellular and Developmental Biology, 1988-92; Assistant Professor, Department of Cellular and Developmental Biology, 1984-88

Johns Hopkins School of Medicine: Research Associate, Department of Cell Biology and Anatomy, 1982-84

Awards, Honors, and Distinctions: Fellow (Inaugural Class), American Society for Cell Biology, American Society for Cell Biology
Newcomb Cleveland Award for the Outstanding Paper in Science, American Association for the Advancement of Science
Elected Fellow of the American Association for the Advancement of Science, American Association for the Advancement of Science Council, November, 2011
Sigma Xi Award for the Best Dissertation at the Unversity of Pennsylvania (1979), Sigma Xi, University of Pennsylvania

Recent Grant Support

Morphogenesis: Biophysics and Genetics of Dorsal Closure, National Institute of General Medical Sciences, 1R35-GM127059-01, 2018/07-2028/06.
Training Program in Developmental and Stem Cell Biology, National Institutes of Health, 2001/05-2027/04.
Cell and Molecular Biology Training Program, National Institute of General Medical Sciences, 2021/07-2026/06.
Genetic and Genomics Training Grant, National Institutes of Health, 2020/07-2025/08.
LUMICKS C-TRAP, National Institutes of Health, 2022/07-2023/07.

Selected Recent Invited Talks: Séminaires du Mecredi - "Cell Sheet Morphogenesis through the Lens of Drosophila's Dorsal Closure", Paris, France, 8 November 2019; The Advanced Light Imaging and Spectroscopy Facility at Duke and the Southeast Ultrafast Conference -"Imaging cell sheet morphogenesis: Mechanistic insights from laser surgical, genetic and molecular genetic manipulated dorsal closure in Drosophila", Durham, NC, 7 October 2019; Soft Condensed Matter Gordon Research Conference - "Molecular and Cellular Dynamics Drive Tissue Development in Drosophila Embryos", New London, NH, 11 August 2019; Toyama Lab and Adjoining Groups at the Mechanobiology Institute - "Molecular and Cellular Dynamics Drive Cell Sheet Morphogenesis: Dorsal Closure as a Model System" , Singapore, 21 June 2019; Chinese Academy of Sciences - "Molecular and Cellular Dynamics Drive Cell Sheet Morphogenesis: Dorsal Closure as a Model System", Beijing, China, 13 June 2019; Department of Molecular, Cell and Developmental Biology - "Morphogenesis: Developmental Biology's Final Frontier viewed through the Lens of Drosophila's Dorsal Closure", University of California, Santa Cruz, 13 November 2017; Mathematical Biosciences Institute Workshop on "The Biological Challenges in Morphogenesis", 17 February 2017; Department of Biological Sciences - "Forces and their regulation in cell sheet morphogenesis: Dorsal Closure in Drosophila as a model system", Mumbai, India, 3 October 2016; Tissue as active matter - Quantitative approaches in developmental biology - "Forces and regulation of cell sheet morphogenesis: Dorsal closure in Drosophila as a model system", Göttingen, Germany, 11 September 2015; National Institute of Child Health and Human Development, Ninth Structural Birth Defects Meeting, Rockville, MD, 8 April 2013; Invited Speaker: Declined because of teaching obligations, Physics of cells - from soft to living matter, Meeting in Hyeres, France, September 06, 2012; Contractility and morphogenesis: Dorsal closure in Drosophila, Santa Cruz Develomental Biology Meeting, August 10, 2012; Dorsal closure in Drosophila as a model for investigating the coordination of contractility and morphogenesis, Banff International Research Station - Alberta, Canada, July 26, 2012; Multidisciplinary Approaches to Morphogenesis: Powering Cell Sheet Movements During Dorsal Closure in Drosophila, Department of Biology, Indiana University, April 19, 2012; Multidisciplinary Approaches to Morphogenesis: Powering Cell Sheet Movements During Dorsal Closure in Drosophila, Department of Cellular and Molecular Medicine, Cleveland Clinic, Cleveland Ohio, March 15, 2012; Future Advances in Drosophila Research: Imaging, Annual Drosophila Research Conference, Chicago, Illinois, March 07, 2012; EMBO Workshop on the Biophysical Mechanisms of Development - "Dorsal Closure: Forces, Molecules and Regulation", Fundacao Calouste Gulbenkian - Oeiras, Portugal, 24 May 2011; CIT Workshop Talk on Biology Gateways, Perkins Library, Duke University, April 29, 2011; Forces for Morphogenesis: Dorsal Closure as a Model System, International Workshop on the Mechanics and Grow of Tissues, from Development to Cancer. Held at the Max Planck Institute for the Physics of Complex Systems, Dresden, Germany, March 24, 2011; Biophysical Contributions to Development in a Post Genomic World:_x000B_Morphogenesis, Development’s Final Frontier, National Institute of Child Health and Human Development Scientific Vision Workshop on Development., February 09, 2011; Forces and Regulation for Cell Sheet Movements in Dorsal Closure, Symposium on the Physics of Living Matter, Cambridge, UK, September 29, 2010; Coordinating Morphogenesis: Fly as a Model System, Department of Molecular Genetics and Cell Biology, University of Chicago, June 1, 2010; Coordinating Morphogenesis: Fly as a Model, Department of Cell Biology, University of North Carolina at Chapel Hill, April 14, 2010; Closing a Hole: Biophysical, Genetic and Pharmacological Analysis of Cell Sheet Morphogenesis, Instituto de Biología Molecular de Barcelona Parc Cientific de Barcelona, Barcelona, Spain, May 28, 2009; Closing a Hole: Biophysical, Genetic and Pharmacological Analysis of Cell Sheet Morphogenesis, Biophysical Mechanisms of Development Instituto Gulbenkian de Ciencia, Lisbon, Portugal, May 24, 2009; Closing a Hole: Biophysical, Genetic and Pharmacological Analysis of Cell Sheet Morphogenesis, Department of Biology, Rensselaer Polytechnical Institute, Troy, N.Y., February 02, 2009; A Myosin Motor Powers Dorsal Closure, Symposium Honoring Bob Adelstein at the National Heart, Blood and Lung Institute, Bethesda, MD, January 16, 2009; The Biophysics and Genetics of Molecular Motors for Morphogenesis and Sensory Perception, Department of Cell Biology, Emory University School of Medicine, May 20, 2008; Biophysics of Tissue Morphogenesis: Genetic, Molecular Genetic and Pharmacological Investigation of Drosophila Dorsal Closure, Department of Develomental and Molecular Biology, Albert Einstein College of Medicine, May 06, 2008; Biophysical, Genetic and Pharmacological Analysis of Morphogenesis: Dorsal Closure as a Model System, Institute for Molecular Biology, University of Oregon, Eugene, Oregon, April 22, 2008; 7th Annual Retreat and Symposium - "Molecular Motors in Cell Biology," "Biophysical and Genetic Analysis of Morphogenesis", University of Pennsylvania - Philadelphia, PA, 12 November 2007; Biophysical and Genetic Analysis of Morphogenesis, Pennsylvania Muscle Institute, University of Pennsylvania, Philadelphia, Pa. 7th Annual Retreat and Symposium “Molecullar Motors in Cell Biology”. Andrew P. Somlyo Lecturer, November 12, 2007; Biophysical and Genetic Analysis of Cell Sheet Morphogenesis: Dorsal Closure as a Model System, Cell, Molecular and Developmental Biology Research Retreat (sponsored by Department of Biology McGill University, Institute for Research in Immunology and Cancer, Universite de Montreal; and Institut de recherches cliniques de Montréal, Universite de Montreal. June 11-13, Mont Gabriel, Ste-Adele, Canada., June 13, 2007; Molecular and Developmental Biology Research Retreat - "Biophysical and Genetic Analysis of Cell Sheet Morphogenesis: Dorsal Closure as a Model System", University of Montreal - Mont Gabriel, Ste-Adele, Canada, 11 June 2007; Biophysical and Genetic Analysis of the Forces that Drive Morphogenesis, Blaffer Seminar Series, Dept. Biochemistry and Molecular Biology, University of Texas M.D. Anderson Cancer Center, April 10, 2007; Genetic Analysis of Cell Sheet Morphogenesis, International workshop on cellular and genomic studies of wound healing, held at Centro de Investigaciones Energeticas, Medioambientales y Technologicas (Ciemat), Madrid, Spain., February 22, 2007; Force Generation by Myosins During Morphogenesis, 2006 Biophysical Discussions, Asilomar Conference Center, Monterey, CA, October 22, 2006; International Biophysical Discussions - "Force Generation by Myosins During Morphogenesis", Asilomar Conference Center - Monterey, CA, 22 October 2006; Human Frontier Science Program Annual Meeting - "Interdisciplinary Research", Paris, France, 3 July 2006; Interdisciplinary Research, Human Frontier Science Program Annual Meeting, Paris, France, July 03, 2006; Biological Sciences - "Biophysical and Genetic Analysis of Morphogenesis", Carnegie Mellon University - Pittsburgh, PA, 12 April 2006; Biophysical and Genetic Analysis of Morphogenesis, Carnegie Mellon University, April 12, 2006; Biophysical and Genetic Analysis of Morphogenesis, British Society of Cell Biology and British Society of Developmental Biology Annual Meeting, York, England, March 21, 2006; British Society of Cell Biology and British Society of Developmental Biology Annual Meeting - "Biophysical and Genetic Analysis of Morphogenesis", York, England, 21 March 2006; Department of Genetics - "Motors for Morphogenesis: Tales of Two Myosins", North Carolina State University - Raleigh, NC, 13 March 2006; Motors for Morphogenesis: Tales of Two Myosins, North Carolina State University, March 13, 2006; Huntsman Cancer Institute - "Myosins Motor Morphogenesis to Close a Hole and Make a Hair", University of Utah - Salt Lake City, UT, 15 February 2006; Myosins Motor Morphogenesis to Close a Hole and Make a Hair, Huntsman Cancer Institute, University of Utah, February 15, 2006; Biophysical, Genetic and Cell Biological Analysis of Morphogenesis, Duke Department of Cell Biology Retreat, September 24, 2005; Duke Department of Cell Biology Retreat - "Biophysical, Genetic and Cell Biological Analysis of Morphogenesis", Wilmington, NC, 24 September 2005; Biophysical and Genetic Analysis of Dorsal Closure Points to a Myosin Motor that Mediates Multiple, Redundant Forces for Morphogenesis, 2005 Gordon Research Conference on Motile & Contractile Systems, July 11, 2005 [htm]; Human Frontier Science Program Awardee's Meeting, Bethesda, MD, June, 2005; Duke Frontiers - "Imaging and Visualization of Morphogenesis In Vivo", Duke University - Durham, NC, 10 May 2005; Imaging and Visualization of Morphogenesis In Vivo, Duke Frontiers 2005, May 10, 2005; Cellular and Molecular Basis of Morphogenesis, Developmental Biology Group, May 06, 2005; Department of Biology - "Cellular and Molecular Basis of Morphogenesis", University of Iowa - Iowa City, IA, 6 May 2005; crinkled encodes an unconventional myosin, Mill Seminar Series, University of Iowa, May 05, 2005; Mill Seminar Series - "Crinkled Encodes an Unconventional Myosin", University of Iowa - Iowa City, IA, 5 May 2005; Imaging Drosophila Development, Workshop Speaker, American Association of Anatomists, San Diego, CA, April 02, 2005; Morphogenesis: Biophysics and Genetics of Dorsal Closure, Symposium Speaker, 49th Annual Meeting Biophysical Society, Long Beach, CA, February 16, 2005; Dan Kiehart, Cincinnati, 8 January 2005; Tails of 3 Myosins: Diverse Biological Function Depends on Actin Based Motor Proteins, University of Iowa, Iowa City, Iowa, 8 January 2005; Morphogenesis: Biophysics and Genetics of Dorsal Closure, Muscle Institute, University of Pennsylvania, Philadelphia, PA, 6 January 2005; Tails of 3 Myosins, Duke University Program in Structural Biology and Biophysics, November 01, 2004; Biophysical Studies on Dorsal Closure, Inoue Symposium, Marine Biological Laboratories, Woods Hole, MA, July 08, 2004; Morphogenesis: Biophysical and Genetic Analysis of Dorsal Closure, Dept. Cell Biology, Kyoto University, Kyoto, Japan, May 20, 2004; Tails of 3 Myosins: Contractility for Diverse Biological Functions, National Institute of Bioscience and Human Technology, Tsukuba, Japan, May 14, 2004; Biophysical and Genetic Analysis of Morphogenesis, Department of Biology, University of Tokyo, May 13, 2004; Morphogenesis: Biophysical and Genetic Analysis of Dorsal Closure, Developmental Biology Program, University of Cincinnati, May 5, 2004; Morphogenesis: Biophysical and Genetic Analysis of Dorsal Closure, Developmental Biology Program, University of Cincinnati, May 05, 2004; Morphogenesis: Biophysics and Genetics of Dorsal Closure, Muscle Institute, University of Pennsylvania, Philadelphia, PA, March 12, 2004; crinkled/myoVIIA Function in Drosophia morphogenesis and hearing, Annual American Society for Cell Biology Meetings, San Francisco, CA, 13 December 2003; Subgroup meeting on "Unconventional Myosins" at the Annual American Society for Cell Biology Meetings, San Francisco, CA, 13 December 2003; Musings on the Mechanisms of Morphogenesis: Modeling Movement and a Myosin Motor, Duke University Thursday Series, Duke University, 16 October 2003; EMBO/FEBS Workshop on Frontiers in Cytoskeleton Research - "Modeling Morphogenesis: Dorsal Closure", Gosnau, Austria, 16 September 2003; Modeling Morphogenesis: Dorsal Closure, EMBO/FEBS Workshop on Frontiers in Cytoskeleton Research, Gosnau, Austria, 16 September 2003; Duke University Nanosciences Symposium, Searle Center, Duke University, May 2003; Duke University Nanosciences Symposium - "Modeling Morphogenesis", Duke University, Searle Center, 1 May 2003; Keystone Meeting on the Dynamics of Cellular Organization - "Modeling Morphogenesis: Laser Microsurgery, Mechanical Jump Experiments and Analysis of Mutants Reveal the Origin of Forces for Dorsal Closure", Taos, NM, 26 February 2003; Modeling Morphogenesis: Laser Microsurgery, Mechanical Jump Experiments and Analysis of Mutants Reveal the Origin of Forces for Dorsal Closure, Keystone Meeting on the Dynamics of Cellular Organizqation, Taos, NM, 26 February 2003; Modeling Morphogenesis, Department of Biology, McGill University, Montreal, Canada, 15 February 2003; Department of Biology - "Modeling Morphogenesis" , University of Texas - Austin, TX, 19 November 2002; Modeling Morphogenesis, Department of Biology, University of Texas, Austin, TX, 19 November 2002; Dorsal Closure, 11th Annual Symposium on Egg to Organ Series, U of MN, St. Paul, MN, 29 September 2002; Euresco Conference on Cellular and Molecular Basis of Regeneration - "Morphogenesis in Drosophila Dorsal Closure", Castelvecchio Pascoli, Italy, 31 August 2002; Santa Cruz Conference on Developmental Biology - "Morphogenesis in Drosophila Dorsal Closure", UC Santa Cruz - Santa Cruz, CA, 15 August 2002; Cell Sheet Morphogenesis, Pollard 60th Birthday Reunion, Yale University, 29 June 2002; Quantitative Modeling of Cell Sheet Morphogenesis, Department of Physics, Duke University (Joint with Glenn Edwards), 4 June 2002; Morphogenesis in Drosophila Dorsal Closure, Department of Biology, New York University, 15 April 2002; International Workshop on Cytoskeleton in Cell Motility, Division and Polarity - "Morphogenesis in Drosophila Dorsal Closure" , National Centre for Biological Science - Bangalore, India, 5 March 2002

Doctoral Theses Directed: Josef D. Franke, (December, 1999 - May, 2005); Marc Champagne, (January, 1994 - November, 2004); Janice Crawford, (May 01, 1994 - May 15, 1999); Zuowei Su, (August 25, 1992 - May 15, 1999); Kevin A. Edwards, (August 25, 1992 - May 15, 1996); Paul Young, (May 01, 1986 - June 20, 1992); Ketchum, Andrew, (May 01, 1985 - June 15, 1991)

Publications (listed separately)

Last modified: 2026/01/13

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