Publications [#160468] of Bernard M Fischer

Papers Published

1. SR White, BM Fischer, BA Marroquin, R Stern, Interleukin-1beta mediates human airway epithelial cell migration via NF-kappaB., American journal of physiology. Lung cellular and molecular physiology, United States, vol. 295 no. 6 (December, 2008), pp. L1018-27, ISSN 1040-0605
   (last updated on 2009/07/30)

   Abstract:
   Migration of airway epithelial cells (AEC) is a necessary component of airway mucosal repair after injury. The cytokine IL-1beta, present in airway inflammation, has protean effects on constituent cells within the mucosa, but its effects on epithelial repair are not known. We examined migration in differentiated primary human AEC grown in air-liquid interface culture for up to 3 wk and in the 16HBE14o(-) cell line. Wounds were created by mechanical abrasion and followed to closure using digital microscopy. Concurrent treatment with IL-1beta (Keywords:
   Asthma • Cell Line • Cell Movement • Epithelial Cells • HSP27 Heat-Shock Proteins • Humans • Interleukin-1beta • MAP Kinase Kinase 4 • MAP Kinase Signaling System • Mitogen-Activated Protein Kinase 1 • Mitogen-Activated Protein Kinase 3 • Phosphorylation • Respiratory Mucosa • STAT3 Transcription Factor • Transcription Factor RelA • cytology • drug effects • drug effects* • metabolism • metabolism* • pharmacology* • physiology