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| Publications [#268758] of G. Allan Johnson
Papers Published
- Johnson, GA; Maronpot, RR, Magnetic resonance microscopy of chemically-induced liver foci.,
Toxicol Pathol, vol. 17 no. 4 Pt 1
(1989),
pp. 613-616, ISSN 0192-6233 [2629098], [doi]
(last updated on 2025/07/07)
Abstract:
Magnetic resonance imaging (MRI) is a new imaging technique used in clinical diagnosis. This paper describes extension of the technique to basic research applications--specifically detecting and characterizing chemically-induced liver neoplasms and foci of cellular alteration. Two systems have been built that allow spatial microscopic resolution--more than 100,000 x greater than that of earlier efforts. Use of spin-lattice (T1) and spin-spin (T2) relaxation times permits detailed characterization of the tissue.
Keywords:
Animals • Carcinogenicity Tests • Diet • Female • Liver • Liver Neoplasms, Experimental • Magnetic Resonance Imaging • Rats • Rats, Inbred F344 • chemically induced • pathology* • ultrastructure
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