Publications [#141998] of Geoffrey S Ginsburg

Papers Published

1. DI Silverman, GS Ginsburg, RC Pasternak, High-density lipoprotein subfractions., The American journal of medicine, UNITED STATES, vol. 94 no. 6 (June, 1993), pp. 636-45, ISSN 0002-9343
   (last updated on 2008/01/15)

   Abstract:
   High-density lipoprotein (HDL) consists of a heterogeneous group of particles defined either by size or by apolipoprotein content. Subfractions of HDL appear to have distinct but interrelated metabolic functions, including facilitation of cholesteryl ester transfer to low- and very-low-density lipoproteins, modulation of triglyceride-rich particle catabolism, and, possibly, removal of cholesterol from peripheral tissues. Like HDL cholesterol, HDL subfractions are widely affected by a variety of factors. Subfractions also are markers for epidemiologic risk for coronary artery disease. Because they provide information about the physiologic processes of cholesterol metabolism, HDL subfractions are emerging as an increasingly important tool in the study of the relationship between lipids and cardiovascular disease.

   Keywords:
   Cholesterol • Humans • Lipoproteins, HDL* • Molecular Weight • Triglycerides • blood • metabolism