Publications [#60964] of George A. Truskey

Papers Published

1. Sharkawy, A. Adam and Klitzman, Bruce and Truskey, George A. and Reichert, W. Monty, Engineering the tissue which encapsulates subcutaneous implants. III. Effective tissue response times, Journal of Biomedical Materials Research, vol. 40 no. 4 (1998), pp. 598 - 605 [(SICI)1097-4636(19980615)40:4<598::AID-JBM11>3.3.CO;2-N]
   (last updated on 2007/04/12)

   Abstract:
   The hypothesis that analyte concentrations within the tissue surrounding porous implants will respond more quickly to change in plasma levels than densely packed, avascular fibrous capsule was studied. The average concentration of lissamine-rhodamine was measured in tissue. A simple two-compartmental model in which a tissue response time constant (τ_p) was extracted. The concentrations of rhodamine within the tissue surrounding the polyvinyl alcohol (PVA) implant were the highest at all time points and responded to change in the plasma rhodamine concentration three times more quickly than fibrous tissue encapsulating nonporous PVA skin.

   Keywords:
   Implants (surgical);Porous materials;Dyes;Polyvinyl alcohols;Polytetrafluoroethylenes;Mathematical models;Blood vessels;Mass transfer;Density (specific gravity);Biocompatibility;