Publications [#279922] of Farshid Guilak

Papers Published

1. Guilak, F, Homing in on a biological joint replacement., Stem Cell Research and Therapy, vol. 1 no. 5 (December, 2010), pp. 40 [21156083], [doi]
   (last updated on 2019/06/30)

   Abstract:
   The use of tissue engineering therapies for treating damaged articular cartilage has traditionally focused on cell-based therapies for the repair of focal chondral or osteochondral defects. A recent study by Lee and colleagues in the Lancet shows exciting proof-of-concept that an acellular scaffold containing transforming growth factor beta 3 can induce homing of cells that regenerate a hyaline-like cartilage surface. These findings provide a glimpse into the possibility that tissue engineering may in fact provide the means for regeneration of an entire joint surface, beyond a simple focal defect in the articular cartilage.