Publications [#279995] of Farshid Guilak

Papers Published

1. Erickson, GR; Guilak, F, Osmotic stress initiates intracellular calcium waves in chondrocytes through extracellular influx and the inositol phosphate pathway, American Society of Mechanical Engineers, Bioengineering Division (Publication) BED, vol. 44 (1999), pp. 43-44, Nashville, TN, USA
   (last updated on 2019/06/30)

   Abstract:
   A study was carried out to examine the hypothesis that osmotic stress initiates a transient increase in the concentration of intracellular calcium ion ([Ca2+]i), and to determine the mechanisms of Ca2+ mobilization in isolated chondrocytes exposed to hypo- and hyper-osmotic stress. Osmotic stress was determined by performing tests within 12 hrs of isolation. The results indicate that both hypo- and hyper-osmotic result in significant increases and oscillations in [Ca2+]i in chondrocytes.

   Keywords:
   Cells;Calcium;Organic compounds;Cartilage;Physiology;Cell culture;Cell immobilization;Osmosis;Kinematics;