Martin Fischer, Research Professor of Chemistry

Contact Info:

Office Location:	2216 French Science Center
Office Phone:	(919) 660-1523
Email Address:

Teaching (Spring 2024):

• ECE 549.01, OPTICS & PHOTONICS SEMINAR SER Synopsis

  Wilkinson 021, W 12:00 PM-01:00 PM

  (also cross-listed as BME 609.01, PHYSICS 549.01)

• ECE 549.01, OPTICS & PHOTONICS SEMINAR SER Synopsis

  Fitzpatrk 1464, W 12:00 PM-01:00 PM

  (also cross-listed as BME 609.01, PHYSICS 549.01)

Education:

Ph.D.	University of Texas, Austin	2001
PhD Physics	The University of Texas at Austin	2001
M.A. in Physics	The University of Texas at Austin	1993
M.A.	University of Texas, Austin	1993
‘Vordiplom’	The University of Freiburg, Germany	1991

Research Interests:

Dr. Fischer’s research focuses on exploring novel nonlinear optical contrast mechanisms for molecular imaging. Nonlinear optical microscopes can provide non-invasive, high-resolution, 3-dimensional images even in highly scattering environments such as biological tissue. Established contrast mechanisms, such as two-photon fluorescence or harmonic generation, can image a range of targets (such as autofluorescent markers or some connective tissue structure), but many of the most molecularly specific nonlinear interactions are harder to measure with power levels one might be willing to put on tissue. In order to use these previously inaccessible interactions as structural and molecular image contrasts we are developing ultrafast laser pulse shaping and pulse shape detection methods that dramatically enhance measurement sensitivity. Applications of these microscopy methods range from imaging biological tissue (mapping structure, endogenous tissue markers, or exogenous contrast agents) to characterization of nanomaterials (such as graphene and gold nanoparticles). The molecular contrast mechanisms we originally developed for biomedical imaging also provide pigment-specific signatures for paints used in historic artwork. Recently we have demonstrated that we can noninvasively image paint layers in historic paintings and we are currently developing microscopy techniques for use in art conservation and conservation science.

Keywords:

Dimerization • Imaging, Three-Dimensional • Laser spectroscopy • Lasers • Microscopy • Molecular Imaging • Multiphoton processes • Muser Mentor • Nonlinear Dynamics • Optical Imaging • Optical Processes • Organometallic Compounds • Scattering, Radiation • Spectrum Analysis

Recent Publications   (More Publications)

1. Grass, D; Beasley, GM; Fischer, MC; Selim, MA; Zhou, Y; Warren, WS, Contrast mechanisms in pump-probe microscopy of melanin., Opt Express, vol. 30 no. 18 (August, 2022), pp. 31852-31862, Optica Publishing Group [doi]  [abs]
2. McKeown Wessler, GC; Wang, T; Sun, J-P; Liao, Y; Fischer, MC; Blum, V; Mitzi, DB, Structural, Optical, and Electronic Properties of Two Quaternary Chalcogenide Semiconductors: Ag₂SrSiS₄ and Ag₂SrGeS₄., Inorganic chemistry, vol. 60 no. 16 (August, 2021), pp. 12206-12217 [doi]  [abs]
3. Jiang, J; Grass, D; Zhou, Y; Warren, WS; Fischer, MC, Beyond intensity modulation: new approaches to pump-probe microscopy., Optics letters, vol. 46 no. 6 (March, 2021), pp. 1474-1477, The Optical Society [doi]  [abs]
4. Fischer, EP; Fischer, MC; Grass, D; Henrion, I; Warren, WS; Westman, E, Low-cost measurement of face mask efficacy for filtering expelled droplets during speech., Sci Adv, vol. 6 no. 36 (September, 2020), pp. eabd3083, American Association for the Advancement of Science (AAAS) [doi]  [abs]
5. Fischer, EP; Fischer, MC; Grass, D; Henrion, I; Warren, WS; Westman, E, Low-cost measurement of facemask efficacy for filtering expelled droplets during speech (June, 2020) [doi]  [abs]