Publications [#234028] of Michael J. Therien

Papers Published

1. Strzalka, J; Xu, T; Tronin, A; Wu, SP; Miloradovic, I; Kuzmenko, I; Gog, T; Therien, MJ; Blasie, JK, Structural studies of amphiphilic 4-helix bundle peptides incorporating designed extended chromophores for nonlinear optical biomolecular materials., Nano letters, vol. 6 no. 11 (November, 2006), pp. 2395-2405, ISSN 1530-6984 [17090064], [doi]
   (last updated on 2026/01/15)

   Abstract:
   Extended conjugated chromophores containing (porphinato)zinc components that exhibit large optical polarizabilities and hyperpolarizabiliites are incorporated into amphiphilic 4-helix bundle peptides via specific axial histidyl ligation of the metal. The bundle's designed amphiphilicity enables vectorial orientation of the chromophore/peptide complex in macroscopic monolayer ensembles. The 4-helix bundle structure is maintained upon incorporation of two different chromophores at stoichiometries of 1-2 per bundle. The axial ligation site appears to effectively control the position of the chromophore along the length of the bundle.