Publications [#330237] of Michael J. Therien

Papers Published

1. Thérien, M; Yves Gauthier, J; Leblanc, Y; Lèger, S; Perrier, H; Prasit, P; Wang, Z, Synthesis of Rofecoxib, (MK 0966, Vioxx® 4-(4′-Methylsulfonylphenyl)-3-phenyl-2(5H)-furanone), a selective and orally active inhibitor of cyclooxygenase-2, Synthesis, vol. 2001 no. 12 (January, 2001), pp. 1778-1779, Georg Thieme Verlag KG [doi]
   (last updated on 2026/01/14)

   Abstract:
   The synthesis of Vioxx® (Rofecoxib, MK 966, 4-(4′methylsulfonylphenyl)-3-phenyl-2(5H)-furanone), a newly FDA approved inhibitor of cyclooxygenase-2, is described.