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Publications [#330250] of Michael J. Therien

Papers Published

  1. Thérien, M; Fitzsimmons, BJ; Scheigets, J; Macdonald, D; Choo, LY; Guay, J; Falgueyret, JP; Riendeau, D, Justicidin E: A new leukotriene biosynthesis inhibitor., Bioorganic and Medicinal Chemistry Letters, vol. 3 no. 10 (January, 1993), pp. 2063-2066, Elsevier BV [doi]
    (last updated on 2026/01/15)

    Abstract:
    Justicidin E, an arylnaphthalene lignan, has been identified as a potent inhibitor of leukotriene biosynthesis by human leukocytes (IC50 = 70 nM) and a non-redox inhibitor of 5-lipoxygenase activity. © 1993.


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