Publications [#132202] of James M Provenzale

Papers Published

1. RM Levy, DC Steffens, DR McQuoid, JM Provenzale, JR MacFall, KR Krishnan, MRI lesion severity and mortality in geriatric depression., The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry, vol. 11 no. 6 (March, 2004), pp. 678-82, ISSN 1064-7481
   (last updated on 2011/07/12)

   Abstract:
   OBJECTIVE: The authors correlated magnetic resonance imaging (MRI) lesion severity and mortality among depressed elderly patients. METHODS: They examined the association of mortality and deep white-matter hyperintensity (DWMH), periventricular hyperintensity (PVH), and subcortical gray-matter hyperintensity (SGH) ratings in 259 subjects. RESULTS: DWMH and PVH were significantly associated with mortality initially, and, in final modeling, DWMH remained significant. CONCLUSIONS: These findings suggest that there is a relationship between cerebrovascular disease severity and mortality among depressed patients. More studies, with larger sample sizes, comparing depressed patients and control subjects are needed to further elucidate this relationship.

   Keywords:
   Aged • Brain • Cerebrovascular Disorders* • Depression • Female • Follow-Up Studies • Humans • Magnetic Resonance Imaging* • Male • complications • complications* • diagnosis • mortality • pathology*