Fitzpatrick Institute for Photonics Fitzpatrick Institute for Photonics
Pratt School of Engineering
Duke University

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Research Interests for Pei Zhong

Research Interests:

Ultrasound-targeted gene delivery and activation; Synergistic combination of high-intensity focused ultrasound (HIFU) and immunotherapy for cancer treatment; Innovations in shock wave lithotripsy (SWL) technology; and Mechanics and bioeffects of acoustic cavitation.

Representative Publications
  1. Z. Hu and X. Y. Yang and Y. Liu and G. N. Sankin and E. C. Pua and M. A. Morse and H. K. Lyerly and T. M. Clay and P. Zhong, Investigation of HIFU-induced anti-tumor immunity in a murine tumor model, Journal Of Translational Medicine, vol. 5 (July, 2007), ISSN 1479-5876
  2. J. I. Iloreta and Y. F. Zhou and G. N. Sankin and P. Zhong and A. J. Szeri, Assessment of shock wave lithotripters via cavitation potential, Physics Of Fluids, vol. 19 no. 8 (August, 2007), ISSN 1070-6631
  3. E. Klaseboer and S. W. Fong and C. K. Turangan and B. C. Khoo and A. J. Szeri and M. L. Calvisi and G. N. Sankin and P. Zhong, Interaction of lithotripter shockwaves with single inertial cavitation bubbles, Journal Of Fluid Mechanics, vol. 593 (December, 2007), pp. 33 -- 56, ISSN 0022-1120
  4. G. N. Sankin and P. Zhong, Interaction between shock wave and single inertial bubbles near an elastic boundary, Physical Review E, vol. 74 no. 4 (October, 2006), ISSN 1539-3755
  5. Y. F. Zhou and L. Zhai and R. Simmons and P. Zhong, Measurement of high intensity focused ultrasound fields by a fiber optic probe hydrophone, Journal Of The Acoustical Society Of America, vol. 120 no. 2 (August, 2006), pp. 676 -- 685, ISSN 0001-4966
  6. Y. B. Liu and T. Kon and C. Y. Li and P. Zhong, High intensity focused ultrasound-induced gene activation in solid tumors, Journal Of The Acoustical Society Of America, vol. 120 no. 1 (July, 2006), pp. 492 -- 501, ISSN 0001-4966
  7. G. N. Sankin and W. N. Simmons and S. L. Zhu and P. Zhong, Shock wave interaction with laser-generated single bubbles, Physical Review Letters, vol. 95 no. 3 (July, 2005), ISSN 0031-9007
  8. Z. L. Hu and X. Y. Yang and Y. B. Liu and M. A. Morse and H. K. Lyerly and T. M. Clay and P. Zhong, Release of endogenous danger signals from HIFU-treated tumor cells and their stimulatory effects on APCs, Biochemical And Biophysical Research Communications, vol. 335 no. 1 (September, 2005), pp. 124 -- 131, ISSN 0006-291X
  9. Y. F. Zhou and F. H. Cocks and G. M. Preminger and P. Zhong, Innovations in shock wave lithotripsy technology: Updates in experimental studies, Journal Of Urology, vol. 172 no. 5 (November, 2004), pp. 1892 -- 1898, ISSN 0022-5347
  10. W. S. Chen and X. C. Lu and Y. B. Liu and P. Zhong, The effect of surface agitation on ultrasound-mediated gene transfer in vitro, Journal Of The Acoustical Society Of America, vol. 116 no. 4 (October, 2004), pp. 2440 -- 2450, ISSN 0001-4966
  11. Y. F. Zhou and P. Zhong, Suppression of large intraluminal bubble expansion in shock wave lithotripsy without compromising stone comminution: Refinement of reflector geometry, Journal Of The Acoustical Society Of America, vol. 113 no. 1 (January, 2003), pp. 586 -- 597, ISSN 0001-4966
  12. X. F. Xi and P. Zhong, Dynamic photoelastic study of the transient stress field in solids during shock wave lithotripsy, Journal Of The Acoustical Society Of America, vol. 109 no. 3 (March, 2001), pp. 1226 -- 1239, ISSN 0001-4966
  13. P. Zhong and Y. F. Zhou and S. L. Zhu, Dynamics of bubble oscillation in constrained media and mechanisms of vessel rupture in SWL, Ultrasound In Medicine And Biology, vol. 27 no. 1 (January, 2001), pp. 119 -- 134, ISSN 0301-5629

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