Publications [#237007] of John H. Reif

Journal articles or Book chapters PUBLISHED

1. Li, H; Park, SH; Reif, JH; LaBean, TH; Yan, H, DNA-templated self-assembly of protein and nanoparticle linear arrays., Journal of the American Chemical Society, vol. 126 no. 2 (January, 2004), pp. 418-419, ISSN 0002-7863 (PubMed PMID: 14719910.) [14719910], [doi]
   (last updated on 2026/01/15)

   Abstract:
   Self-assembling DNA tiling lattices represent a versatile system for nanoscale construction. Self-assembled DNA arrays provide an excellent template for spatially positioning other molecules with increased relative precision and programmability. Here we report an experiment using a linear array of DNA triple crossover tiles to controllably template the self-assembly of single-layer or double-layer linear arrays of streptavidin molecules and streptavidin-conjugated nanogold particles through biotin-streptavidin interaction. The organization of streptavidin and its conjugated gold nanoparticles into periodic arrays was visualized by atomic force microscopy and scanning electron microscopy.