Publications [#237035] of John H. Reif

Journal articles or Book chapters PUBLISHED

1. Reif, JH; Labean, TH, Autonomous programmable biomolecular devices using self-assembled DNA nanostructures, Communications of the ACM, vol. 50 no. 9 (September, 2007), pp. 46-53, Association for Computing Machinery (ACM), ISSN 0001-0782 [doi]
   (last updated on 2026/01/14)

   Abstract:
   Recent developments in bio-DNA computer science techniques and methods for the development of autonomous programmable biomolecular devices based on self-assembled DNA nanostructures are reviewed. Molecular-scale devices using DNA nanostructures are engineered to have various capabilities such as execution of molecular-scale computation, use as scaffolds or templates for further assembly of other materials, and robotic movement and molecular transport. DNA nanostructures encode the Hamiltonian path after combining in a teat tube and cooling. Methods for autonomous execution of a sequence of finite-state operations are based on algorithmic self-assembly. Autonomous execution of a DNA sequence of finite-state transition is based on a linear DNA nanostructure whose sequence encodes the inputs and executes a series of steps that digest the DNA nanostructure from one end.