Publications [#237051] of John H. Reif

Journal articles or Book chapters PUBLISHED

1. Reif, JH, Keynote: DNA-based molecular devices, 2011 IEEE 1st International Conference on Computational Advances in Bio and Medical Sciences Iccabs 2011 (April, 2011), pp. 3, IEEE [doi]
   (last updated on 2026/01/15)

   Abstract:
   We overview recent work in the field of DNA-based autonomous biomolecular devices. We particularly emphasize molecular assemblies and molecular devices that are (i) self-assembled: that is they assemble into DNA nanostructures in one stage without explicit external control, (ii) programmable: the tasks the molecular devices execute can be modified without an entire redesign and (ii) autonomous: they operate without external mediation (e.g. thermal-cycling). We describe recent experimental progress in DNA-based autonomous biomolecular devices that achieve: 2D patterning, computation, amplified sensing, and molecular nano-scale transport. These have taken the technology from a state of intriguing possibilities into demonstrated capabilities of quickly increasing scale, and we describe a number of very promising applications in the biomedical industry. © 2011 IEEE.