Publications [#262856] of Tuan Vo-Dinh

Papers Published

1. Wabuyele, MB; Yan, F; Griffin, GD; Vo-Dinh, T, Surface-enhanced Raman scattering molecular nanoprobes, Progress in Biomedical Optics and Imaging Proceedings of SPIE, vol. 5692 (July, 2005), pp. 209-215, SPIE, San Jose, CA, United States, ISSN 1605-7422 [12.604447], [doi]
   (last updated on 2026/01/21)

   Abstract:
   Nanoparticles are increasingly finding a wide application in the biological studies due to their unique physical and chemical properties. Colloidal nanoparticles are efficient substrate that exhibit surface-enhanced Raman scattering (SERS) phenomenon by enhancing the scattering cross-sections of conjugated Raman active molecules thus enabling highly sensitive biological probes. However, biological and medical applications would require nanoparticles to be conjugated to biomolecules. A universal approach for conjugation of mercarptoacetic acid-capped silver nanoparticles to biomolecules is described. The surface functionalized silver colloids were labeled with a Raman active dye and used for cellular imaging. We also described the use of silver nanoparticle to develop a new class of SERS nanoprobes for molecular recognition and detection of specific nucleic acid sequences.

   Keywords:
   Nanostructured materials;Silver;Cell culture;Fluorescence;Bandwidth;Colloids;Chemical analysis;