Publications [#262899] of Tuan Vo-Dinh

Papers Published

1. Vo-Dinh, T; Panjehpour, M; Overholt, BF; Julius, C; Overholt, S; Phan, MN, Laser-induced fluorescence for the detection of esophageal and skin cancer, Proceedings of SPIE the International Society for Optical Engineering, vol. 4958 (December, 2003), pp. 67-70, SPIE, San Jose, CA, United States [12.488678], [doi]
   (last updated on 2026/01/21)

   Abstract:
   Laser-induced fluorescence (LIF) is used for in-vivo cancer diagnosis of the esophagus and skin cancer. For esophageal measurements a fiberoptic probe inserted through an endoscope was used. Autofluorescence of normal and malignant tissues were measured directly on patient skin without requiring an endoscope. Measurement of the fluorescence signal from the tissue was performed using laser excitation at 410 nm. The methodology was applied to differentiate normal and malignant tumors of the esophagus and malignant skin lesions. The results of this LIF approach were compared with histopathology results of the biopsy samples and indicated excellent agreement in the classification of normal and malignant tumors for the samples investigated.

   Keywords:
   Laser tissue interaction;Oncology;Gastroenterology;Skin;Fiber optics;Endoscopy;Tumors;Biopsy;Photodiodes;