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| Publications [#263019] of Tuan Vo-Dinh
Papers Published
- Yan, F; Wabuyele, MB; Griffin, GD; Vo-Dinh, T, Metallic nanostructures for plasmonic sensors using surface-enhanced fluorescence and Raman detection,
Proceedings of SPIE the International Society for Optical Engineering, vol. 5327
(November, 2004),
pp. 53-59, SPIE, San Jose, CA, United States, ISSN 0277-786X [12.542455], [doi]
(last updated on 2026/01/19)
Abstract: We present the fabrication and characterization of silver island films with SiO 2 coatings for application in plasmonic sensors based on surface-enhanced fluorescence and Raman detection. The emission spectral properties of goat anti-mouse immunoglobulin (IgG) F(ab′) 2 labeled with one or two fluorescein residues were examined on substrates with metallic silver islands. The self-quenching of fluorescein emission was mostly eliminated when this antibody fragment was held 60-90 A from the surface of metallic silver islands, and our preliminary experiments demonstrated an 8-fold emission intensity increase. Similar surfaces were also examined for surface-enhanced Raman analysis of Rhodamine 123, a potential drug for photodynamic therapy.
Keywords: Silicon compounds;Charge coupled devices;Immunology;Photodynamic therapy;Raman scattering;Physical vapor deposition;Surface plasmon resonance;Electromagnetic field effects;
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