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| Publications [#235003] of Weitao Yang
Journal Articles
- Kasper, AC; Moon, EJ; Hu, X; Park, Y; Wooten, CM; Kim, H; Yang, W; Dewhirst, MW; Hong, J, Analysis of HIF-1 inhibition by manassantin A and analogues with modified tetrahydrofuran configurations.,
Bioorg Med Chem Lett, vol. 19 no. 14
(July, 2009),
pp. 3783-3786 [19423348], [doi]
(last updated on 2026/01/17)
Abstract: We have shown that manassantin A downregulated the HIF-1alpha expression and inhibited the secretion of VEGF. We have also demonstrated that the 2,3-cis-3,4-trans-4,5-cis-configuration of the tetrahydrofuran is critical to the HIF-1 inhibition of manassantin A.
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