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| Publications [#235017] of Weitao Yang
Journal Articles
- Kim, D; Lee, H; Kim, KW; Park, J; Kim, H; Kim, S; Hu, X; Yang, W; Hong, J, A general strategy for construction of both 2,6-cis- and 2,6-trans-disubstituted tetrahydropyrans: substrate-controlled asymmetric total synthesis of (+)-scanlonenyne,
Angewandte Chemie International Edition, vol. 47 no. 22
(2008),
pp. 4200-4203, ISSN 1433-7851 [doi]
(last updated on 2026/01/16)
Abstract: (Chemical Equation Presented) A synthetic three-ring circus: The asymmetric total synthesis of (+)-scanlonenyne includes a sequential epimerization and intramolecular hetero-Michael addition for the construction of pyrano-γ-lactones (see scheme; DBU: 1,8-diazabicyclo[5.4.0]undec-7-ene), a highly efficient one-carbon homologation/bromination strategy, and a Weinreb ketone synthesis/cross-metathesis protocol for the elaboration of a sensitive side chain. © 2008 Wiley-VCH Verlag GmbH & Co. KGaA.
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