Publications [#342721] of Weitao Yang

Journal Articles

1. Yao, Y; Yang, W; Wang, C; Gu, F; Yang, D, Radical Addition of Thiols to Oxa(aza)bicyclic Alkenes in Water, Asian Journal of Organic Chemistry, vol. 8 no. 4 (April, 2019), pp. 506-513 [doi]
   (last updated on 2026/01/17)

   Abstract:
   An air-promoted radical addition reaction of various thiols to oxa(aza)bicyclic alkenes is reported, leading to the corresponding exo adducts in good to excellent yields (up to 99%) in water without the use of any metal catalyst, photoredox catalyst or radical initiator reagent under mild conditions. The reaction has a wide scopeof oxa(aza)bicyclic alkenes and thiols, which provides an easy and clean way for the direct preparation of thioethers. A proposed mechanism of an exo free radical attacking the double bond of an oxa(aza)bicyclic alkene was investigated by DFT calculations of stepwise reaction pathways and control experiments.