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Pratt School of Engineering
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Publications [#358013] of Weitao Yang

Journal Articles

  1. Yao, Y; Lin, Q; Yang, W; Yang, W; Gu, F; Guo, W; Yang, D, Cobalt(II)-Catalyzed [4+2] Annulation of Picolinamides with Alkynes via C-H Bond Activation., Chemistry (Weinheim an der Bergstrasse, Germany), vol. 26 no. 25 (May, 2020), pp. 5607-5610 [doi]
    (last updated on 2026/01/16)

    Abstract:
    A cobalt(II)-catalyzed [4+2] annulation of picolinamides with alkynes via C-H bond activation has been developed. The operationally simple annulation reaction allows for the synthesis of acyl-substituted 1H-benzoquinoline bearing multiple aromatic rings (up to 96 % yield) without co-oxidant or other oxidation factors under mild conditions. Several control experiments were carried out. This practical [4+2] annulation provides an efficient route to access highly functionalized compounds.


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