Publications [#65237] of Michael R. Zalutsky

Papers Published

1. Turkington, T.G. and Zalutsky, M.R. and Jaszczak, R.J. and Garg, P.K. and Vaidyanathan, G. and Coleman, R.E., Measuring astatine-211 distributions with SPECT, Phys. Med. Biol. (UK), vol. 38 no. 8 (1993), pp. 1121 - 30 [010]
   (last updated on 2007/04/15)

   Abstract:
   The authors have investigated standard SPECT techniques (rotating gamma cameras, multi-hole collimators, and filtered backprojection reconstruction) for imaging astatine-211 distributions. Since ²¹¹At emits alpha particles, this nuclide has potential for use in radiotherapy. The capability of imaging this nuclide would allow in vivo evaluation of the distribution and stability of potential ²¹¹At-labelled radiotherapeutic agents. ²¹¹At decay yields X-rays in the 77-92 keV range in addition to 500-900 keV gamma rays. The study evaluates the feasibility of SPECT imaging using the X-ray emissions of ²¹¹At. The authors have evaluated several collimators, with the determination that the medium-energy collimators are suitable, with 7% penetration (uncollimated counts versus collimated counts). Several phantoms were imaged and attenuation coefficients were measured (narrow-beam μ=0.182 cm^-1 for 77-80 keV X-rays in water)

   Keywords:
   astatine;computerised tomography;radioisotope scanning and imaging;