Publications [#260816] of Ashutosh Chilkoti

Papers Published

1. MacEwan, SR; Chilkoti, A, Elastin-like polypeptides: biomedical applications of tunable biopolymers., Biopolymers, vol. 94 no. 1 (January, 2010), pp. 60-77, ISSN 0006-3525 [20091871], [doi]
   (last updated on 2026/01/15)

   Abstract:
   Artificial repetitive polypeptides have grown in popularity as a bioinspired alternative to synthetic polymers. The genetically encoded synthesis, monodispersity, potential lack of toxicity, and biocompatibility are attractive features of these biopolymers for biological applications. Elastin-like polypeptides (ELPs) are one such class of biopolymers that are of particular interest because of their "smart"-stimuli responsive-properties. Herein, we discuss the genetically encoded design and recombinant synthesis of ELPs that enable precise control of their physicochemical properties and which have led to a wide range of biomedical applications of these biopolymers in the last decade.