Publications [#63231] of Mark W. Dewhirst

Papers Published

1. Stauffer, P.R. and Cetas, T.C. and Fletcher, A.M. and DeYoung, D.W. and Dewhirst, M.W. and Oleson, J.R. and Roemer, R.B., Observations on the use of ferromagnetic implants for inducing hyperthermia, IEEE Trans. Biomed. Eng. (USA), vol. BME-31 no. 1 (1984), pp. 76 - 90
   (last updated on 2007/04/14)

   Abstract:
   Magnetic induction heating of ferromagnetic implants can be used to produce highly localised hyperthermia in deep-seated tumors. The authors discuss the physical parameters which characterize this method and give illustrations from initial clinical investigations in animals. The physical parameters studied include magnetic field strength, frequency, load size, field uniformity, coil designs, and the heating potential of implant materials and configurations. Calculated maximum heating frequency is on the order of 500 kHz for large abdomen, and 1.9 MHz for smaller loads, such as the human cross-sectional loads, such as the human brain. An experimental technique is introduced for accurate quantitative evaluation of the heating potentials of ferromagnetic materials in a gelled phantom medium. These data are analyzed in terms of heating efficiency per unit implant length. A brief discussion of techniques of implanting the ferromagnetic materials is also given. Finally, several in vivo animal studies are presented to illustrate the use of the technique for treating tumors in pelvis, thorax, oral-pharynx, and brain tissues

   Keywords:
   biothermics;ferromagnetism;radiation therapy;radiofrequency heating;