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Publications [#61035] of Roger C. Barr

Papers Published

  1. Barr, R.C. and Plonsey, R., Propagation of excitation in idealized anisotropic two-dimensional tissue, Biophys. J. (USA), vol. 45 no. 6 (1984), pp. 1191 - 202
    (last updated on 2007/04/12)

    Abstract:
    Reports on a simulation of propagation for anisotropic two-dimensional cardiac tissue. The tissue structure assumed was that of a Hodgkin-Huxley membrane separating inside and outside anisotropic media, obeying Ohm's law in each case. Membrane current was found by an integral expression involving partial spatial derivatives of Vm weighted by a function of distance. Numerical solutions for transmembrane voltage as a function of time following excitation at a single central site were computed using an algorithm that examined only the portion of the tissue undergoing excitation at each moment; thereby, the number of calculations required was reduced to a large but achievable number. Results are shown for several combinations of the four conductivity values

    Keywords:
    bioelectric phenomena;biomembranes;cardiology;digital simulation;


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